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Interleukin-3: a putative protective factor against breast cancer which is secreted by male but not female breast fibroblasts.
The enzyme 17 beta-hydroxysteroid dehydrogenase (17-HSD) is a key regulator of intracellular 17 beta-estradiol (E2), which is associated with breast cancer and is influenced by paracrine factors released by breast-cancer fibroblasts. Since …