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Surgical Outcomes of Implant versus Autologous Breast Reconstruction in Patients with Previous Breast-Conserving Surgery and Radiotherapy.
[BACKGROUND] Postmastectomy breast reconstruction in patients with a history of breast-conserving surgery (BCS) and radiotherapy is challenging, with a paucity of literature on the outcomes of different breast reconstructive techniques. The…
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Outcomes of Autologous Free Flap Reconstruction Following Infected Device Explantation.
[BACKGROUND] Following implant-based breast reconstruction (IBR) infection and explantation, autologous reconstruction is a common option for patients who desire further reconstruction. However, few data exist about the outcomes of seconda…
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Breast Implant-associated Anaplastic Large Cell Lymphoma: A Prospective Series of 52 Patients.
[OBJECTIVE] We sought to evaluate patients at a single academic institution in a prospective manner to report patient presentation, clinical course, treatment, and outcomes in breast implant ALCL patients. [BACKGROUND] Breast implant-assoc…
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Microvascular Free Tissue Transfer for Reconstruction of Complex Abdominal Wall Defects.
[SUMMARY] Patients with significant loss of abdominal wall soft tissue represent a reconstructive challenge. The purpose of this study was to describe the authors' experience using microvascular free tissue transfer to repair complex abdomi…
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Comparing Donor Site Morbidity for Autologous Breast Reconstruction: Thigh vs. Abdomen.
[UNLABELLED] Although abdominally-based free flaps have long been the gold standard, the profunda artery perforator (PAP) flap has emerged as an important alternative option for autologous breast reconstruction. The aim of this study was to…
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Surgical and Patient-Reported Outcomes of Autologous versus Implant-Based Reconstruction following Infected Breast Device Explantation.
[BACKGROUND] Implant-based breast reconstruction infections often require implant explantation. Whereas some plastic surgeons pursue autologous reconstruction following the first implant-based breast reconstruction failure caused by infecti…
- Podcasts in Plastic Surgery: Where Do We Currently Stand?
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Impact of Predatory Journals in Plastic Surgery Literature: Researchers Beware.
[BACKGROUND] Predatory journals have exploited the open access publishing model and are considered as a major threat to the integrity of scientific research. The goal of this study was to characterize predatory publishing practices in plast…
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Master's Degrees Among Academic Plastic Surgeons and Plastic Surgery Residents: What Are the Trends?
[BACKGROUND] As more plastic surgery clinicians pursue advanced degrees and strive to become stronger physician-scientists, an objective understanding of how such degrees influence careers becomes important. We hypothesized that having a ma…
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Advising patients about breast implant associated anaplastic large cell lymphoma.
The United States Food and Drug Administration (FDA) recently recognized the necessity for improved patient education and public awareness of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). BIA-ALCL is an uncommon T-cel…
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Management of Symptomatic Patients with Textured Implants.
Proper management of symptomatic textured implant patients is critical to identify and treat associated oncologic disease. Textured surface breast implants were first introduced more than 50 years ago in an effort to decrease high rates of …
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The Profunda Artery Perforator Flap: A Versatile Option for Head and Neck Reconstruction.
[BACKGROUND] Although the profunda artery perforator flap has gained popularity in breast reconstruction, it has not been well described for reconstruction of head and neck defects. The authors report their experience with free profunda art…
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Robotic DIEP Patient Selection: Analysis of CT Angiography.
[BACKGROUND] Preoperative CTA is widely used and extensively studied for planning of DIEP flap breast reconstruction. However, its utility in planning robotic DIEP harvest is undescribed. [METHODS] The authors conducted a retrospective stu…
- Hot Topics in Reconstructive Surgery.
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Validation of a CD30 Enzyme-Linked Immunosorbant Assay for the Rapid Detection of Breast Implant-Associated Anaplastic Large Cell Lymphoma.
[BACKGROUND] Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an uncommon type of non-Hodgkin lymphoma occurring in the fluid or capsule adjacent to textured breast implants. Diagnosis of BIA-ALCL of symptomatic patien…
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Characteristics and Treatment of Advanced Breast Implant-Associated Anaplastic Large Cell Lymphoma.
[BACKGROUND] Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) most commonly follows an indolent course; however, a subset of patients display more advanced disease marked by recurrent and disseminated growth refractory to…
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Differences in Human Leukocyte Antigen Expression Between Breast Implant-Associated Anaplastic Large Cell Lymphoma Patients and the General Population.
[BACKGROUND] Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an uncommon T-cell lymphoma associated with textured-surface breast implants. Human leukocyte antigen (HLA) polymorphisms have been described with other for…
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US FDA Breast Implant Postapproval Studies: Long-term Outcomes in 99,993 Patients.
[OBJECTIVE] To analyze the long-term safety and efficacy outcomes of patients with breast implants. [SUMMARY BACKGROUND DATA] Research is ongoing regarding the safety of silicone breast implants. Despite the number of patients with breast …
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Breast Reconstruction Following Breast Implant-Associated Anaplastic Large Cell Lymphoma.
[BACKGROUND] Standard of care treatment of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) involves surgical resection with implant removal and complete capsulectomy. We report a case series of BIA-ALCL reconstruction wi…
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Factors Correlating With Microsurgical Performance: A Clinical and Experimental Study.
[BACKGROUND] Microsurgery is one the most complex surgical skills to master. The factors correlating with microsurgical performance, however, are poorly understood. Understanding these factors will aid in the training and assessment of micr…
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U.S. Epidemiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma.
[BACKGROUND] Breast implant-associated anaplastic large cell lymphoma (ALCL) is a distinctive type of T-cell lymphoma that arises around breast implants. Although rare, all cases with adequate history have involved a textured breast implant…
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Global Adverse Event Reports of Breast Implant-Associated ALCL: An International Review of 40 Government Authority Databases.
[BACKGROUND] Tracking world cases of breast implant-associated anaplastic large cell lymphoma (ALCL) is currently limited to patient registries at a few academic centers, dependent upon patient referral and case reports in the literature. T…
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Complete Surgical Excision Is Essential for the Management of Patients With Breast Implant-Associated Anaplastic Large-Cell Lymphoma.
[PURPOSE] Breast implant-associated anaplastic large-cell lymphoma (BI-ALCL) is a rare type of T-cell lymphoma that arises around breast implants. The optimal management of this disease has not been established. The goal of this study is to…
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Breast Implant Informed Consent Should Include the Risk of Anaplastic Large Cell Lymphoma.
Breast implant-associated anaplastic large cell lymphoma (ALCL) is a rare T-cell lymphoma arising around breast implants. Public awareness has increased following a safety communication warning of the association of breast implant-associate…
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[DOTAP liposome-mediated transfection of human adipose-derived stemcells with pIRES2-EGFP-VEGF plasmid and target gene expression].
To explore liposome-mediated transfection of human adipose-derived stem cells (hASCs) with vascular endothelial growth factor(VEGF) gene and to investigate the expression of VEGF after transfection.Lipoaspirate was digested using collagenas…