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Clinical Practice Guidelines for the Diagnosis, Management, and Surveillance of -Related Autosomal Dominant Leukodystrophy.
[BACKGROUND AND OBJECTIVES] There is limited published evidence to guide the diagnosis and management of -related autosomal dominant leukodystrophy (ADLD), an adult-onset progressive neurodegenerative genetic disorder caused by pathogenic v…
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Dysphagia in multiple system atrophy consensus statement on diagnosis, prognosis and treatment.
Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by a combination of autonomic failure plus cerebellar syndrome and/or parkinsonism. Dysphagia is a frequent and disabling symptom in MSA and its occurrence within 5…
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A real-world study on unmet medical needs in triptan-treated migraine: prevalence, preventive therapies and triptan use modification from a large Italian population along two years.
[BACKGROUND] Although migraine is a disabling neurological condition that causes important disability, it remains an area of underdiagnosis and undertreatment worldwide. The aim of this study was to depict the burden of the unmet medical ne…
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Optimizing the long-term management of chronic migraine with onabotulinumtoxinA in real life.
Management of chronic migraine is challenging. OnabotulinumtoxinA (OBT-A) is the only medication licensed for prevention of chronic migraine, and has been widely adopted in clinical practice. Limited data is available on its long-term use. …
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Onabotulinumtoxin A for the management of chronic migraine in current clinical practice: results of a survey of sixty-three Italian headache centers.
[BACKGROUND] Chronic migraine is a complex clinical condition often undertreated. Onabotulinumtoxin A (OBT-A) was approved in Italy in 2013 for symptom relief in patients with chronic migraine who have failed, or do not tolerate, oral proph…