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Halting hyaluronidase activity with hyaluronan-based nanohydrogels: development of versatile injectable formulations.
Hyaluronan (HA) is among the most used biopolymers for viscosupplementation and dermocosmetics. However, the current injectable HA-based formulations present relevant limitations: I) unmodified HA is quickly degraded by endogenous hyaluroni…