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Risk factors for capsular contracture: a study of 91 537 breast implants over 6 years from the Australian Breast Device Registry.
[BACKGROUND] Capsular Contracture (CC) is a key downstream complication of breast implant surgery captured by breast implant registries worldwide. A number of factors have a been linked to CC development including smooth implants and bacter…
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Preventing Bacterial Contamination of Breast Implants Using Infection Mitigation Techniques: An In Vitro Study.
[BACKGROUND] Bacterial contamination of implants has been linked to biofilm formation and subsequent infection, capsular contracture, and breast implant-associated anaplastic large cell lymphoma. Reducing contamination during implant insert…
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The Low-Abundance Plasma Proteome Reveals Differentially Abundant Proteins Associated with Breast Implant Capsular Contracture: A Pilot Study.
Capsular contracture (CC) is one of the most common postoperative complications associated with breast implant-associated infections. The mechanisms that lead to CC remain poorly understood. Plasma is an ideal biospecimen for early proteomi…
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Randomized Controlled Trial to Assess Negative Pressure Wound Therapy versus Standard-of-care Dressings in Breast Surgery: A Pilot Study.
[BACKGROUND] Standard breast reduction dressings such as Prineo are used to cover surgical wounds, in combination with a binder or support bra. The Prevena Restor BellaForm is a negative pressure wound therapy dressing that covers the entir…
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Prospective Study of Clinical Outcomes From a Breast Implant Assessment Service.
[BACKGROUND] Breast augmentation remains the commonest cosmetic surgical procedure worldwide, in spite of recent regulatory action. [OBJECTIVES] The aim of this study was to evaluate women with breast implants attending a breast implant as…
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What are the likely causes of breast implant associated anaplastic large cell lymphoma (BIA-ALCL)?
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a CD30-positive, anaplastic lymphoma kinase-negative T-cell lymphoma. Where implant history is known, all confirmed cases to date have occurred in patients with exposure…
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Gram-Negative Bacterial Lipopolysaccharide Promotes Tumor Cell Proliferation in Breast Implant-Associated Anaplastic Large-Cell Lymphoma.
Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) is a distinct malignancy associated with textured breast implants. We investigated whether bacteria could trigger the activation and multiplication of BIA-ALCL cells in vit…
- Adverse Events Associated with Breast Implants: The Role of Bacterial Infection and Biofilm.
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The ECLiPSE Procedure as an Alternative to Mastopexy following Implant Removal.
[UNLABELLED] With the rise in number of breast implant removals for a variety of indications, strategies to improve aesthetic outcomes, while minimizing scars and operating time, will prove to be of benefit. We present here a novel periareo…
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Breast Implant-Associated Anaplastic Large Cell Lymphoma in Australia: A Longitudinal Study of Implant and Other Related Risk Factors.
[BACKGROUND] Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an emerging cancer that has been linked to the use of textured devices. The recent increase in number and frequency of cases has led to worldwide regulatory…
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Etiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL): Current Directions in Research.
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a CD30-positive, anaplastic lymphoma kinase-negative T-cell lymphoma. Where implant history is known, all confirmed cases to date have occurred in patients with exposure…
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The Reversed Glove Sleeve: A Readily Available and Cost-effective Way to Achieve "No Touch" Breast Implant Insertion.
The reversed glove sleeve technique is a simple, available, reproducible, and cost-effective method of achieving "no touch" breast implant insertion. It allows a new glove to be used for each side, thus reducing the risk of contamination by…
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Optimizing Breast Pocket Irrigation: The Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) Era.
[BACKGROUND] Specific antimicrobial breast pocket irrigations have been proven over the past 20 years to reduce the incidence of capsular contracture by a factor of 10, and the emergence of breast implant-associated anaplastic large cell ly…
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Theories of Etiopathogenesis of Breast Implant-Associated Anaplastic Large Cell Lymphoma.
Breast implant-associated anaplastic large cell lymphoma is a malignancy of T lymphocytes that is associated with the use of textured breast implants in both esthetic and reconstructive surgeries. Patients typically present with a delayed s…
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Current Risk Estimate of Breast Implant-Associated Anaplastic Large Cell Lymphoma in Textured Breast Implants.
[BACKGROUND] With breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) now accepted as a unique (iatrogenic) subtype of ALCL directly associated with textured breast implants, we are now at a point where a sound epidemiologic…
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The Epidemiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma in Australia and New Zealand Confirms the Highest Risk for Grade 4 Surface Breast Implants.
[BACKGROUND] The epidemiology and implant-specific risk for breast implant-associated (BIA) anaplastic large cell lymphoma (ALCL) has been previously reported for Australia and New Zealand. The authors now present updated data and risk asse…
- Commentary on: Evaluation of Antibiotic-Impregnated Mesh in Preventing the Recurrence of Capsular Contracture.
- Commentary on: Back to Basics: Could the Preoperative Skin Antiseptic Agent Help Prevent Biofilm-Related Capsular Contracture?
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A Comparative Trial of Incisional Negative-Pressure Wound Therapy in Abdominoplasty.
The risk for minor local complications for abdominoplasty remains high despite advances in strategies in recent years. The most common complication is the formation of seroma with reported rates ranging from 15% to 40%. The use of incisiona…
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Breast Reconstruction Following Breast Implant-Associated Anaplastic Large Cell Lymphoma.
[BACKGROUND] Standard of care treatment of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) involves surgical resection with implant removal and complete capsulectomy. We report a case series of BIA-ALCL reconstruction wi…
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Breast Implant Selection: Consensus Recommendations Using a Modified Delphi Method.
[BACKGROUND] Geographical differences in breast implant selection approaches exist, and clinical data to guide the process are limited. Developing knowledge of implant-related risk factors further complicates the process. This analysis aime…
- Introduction to "A Review of Breast Implant-Associated Anaplastic Large Cell Lymphoma".
- Reply: Breast Implant-Associated Anaplastic Large Cell Lymphoma in Australia and New Zealand: High-Surface-Area Textured Implants Are Associated with Increased Risk.
- Commentary on: Breast Erythema in a Patient With Breast Implant-Associated Anaplastic Large Cell Lymphoma: A Case Report Discussing Cutaneous Manifestations.
- Letter to Editor: Fleming D, Stone J, Tansley P. Spontaneous Regression and Resolution of Breast Implant-Associated Anaplastic Large Cell Lymphoma: Implications for Research, Diagnosis and Clinical Management, APS 2018.
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Breast Implant-Associated Anaplastic Large Cell Lymphoma.
[PURPOSE OF REVIEW] Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a recently recognised malignancy of T lymphocytes exclusively associated with textured breast implants. This review aims to evaluate existing theorie…
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The Functional Influence of Breast Implant Outer Shell Morphology on Bacterial Attachment and Growth.
[BACKGROUND] The introduction of texture to the outer shell of breast implants was aimed at increasing tissue incorporation and reducing capsular contracture. It has also been shown that textured surfaces promote a higher growth of bacteria…
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Global Adverse Event Reports of Breast Implant-Associated ALCL: An International Review of 40 Government Authority Databases.
[BACKGROUND] Tracking world cases of breast implant-associated anaplastic large cell lymphoma (ALCL) is currently limited to patient registries at a few academic centers, dependent upon patient referral and case reports in the literature. T…
- Discussion: U.S. Epidemiology of Breast Implant-Associated Anaplastic Large-Cell Lymphoma.
- Commentary on: CD30+ T Cells in Late Seroma May Not Be Diagnostic of Breast Implant-Associated Anaplastic Large Cell Lymphoma.