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8건 · 최신순-
Free Flap Reconstruction in Burns: A Systematic Review of Current Practices and Evidence.
[BACKGROUND] The use of microsurgery remains extremely limited in burn management despite offering an alternative in cases where conventional burn reconstruction techniques fall short. This systematic review aims to evaluate the success of …
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MicroRNA engineered umbilical cord stem cell-derived exosomes direct tendon regeneration by mTOR signaling.
[BACKGROUND] Exosomes are extracellular vesicles of nano-structures and represent an emerging nano-scale acellular therapy in recent years. Tendon regeneration is a sophisticated process in the field of microsurgery due to its poor natural …
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[Effectiveness of free anterolateral thigh flap in repairing hand twist trauma combined with forearm main vascular injury].
[OBJECTIVE] To evaluate the effectiveness of free anterolateral thigh flap in repairing hand twist trauma combined with forearm main vascular injury. [METHODS] Between February 2016 and March 2020, 14 patients with hand twist trauma combin…
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Mechanism of Cdk5-synaptophysin-SNARE pathway in acute and chronic inflammatory pain.
[PURPOSE] Currently, there is no favorable treatment plan for inflammatory pain, so exploring new analgesics is still a research hotspot in this area. Cyclin-dependent protein kinase 5 (Cdk5) is a pain-related protein kinase, but its mechan…
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Submental island flap vs free tissue transfer in oral cavity reconstruction: Systematic review and meta-analysis.
[BACKGROUND] The submental island flap (SMIF) is frequently utilized as an alternative to free tissue transfer (FTT) in oral cavity reconstruction. [METHODS] Studies directly comparing SMIF and FTT for oral cavity defects were included. Da…
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Intra-articular injection of Botulinum toxin A reduces neurogenic inflammation in CFA-induced arthritic rat model.
Currently, administration of Botulinum toxin Type A (BoNT/A) to treat arthritic pain has promising efficacy in clinical research. However, the mechanisms underlying anti-neurogenic inflammation mediated by BoNT/A remains unclear. The aim of…
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Botulinum toxin type A reduces TRPV1 expression in the dorsal root ganglion in rats with adjuvant-arthritis pain.
Arthritis pain affects people's long-term health, and recent studies have demonstrated that transient receptor potential vanilloid type 1 (TRPV1) plays a crucial role in arthritis pain. In addition, Pre-clinical evidence indicated that botu…
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Activation of host wound responses in breast cancer microenvironment.
[PURPOSE] Cancer progression is mediated by processes that are also important in wound repair. As a result, cancers have been conceptualized as overhealing wounds or "wounds that do not heal," and gene expression signatures reflective of wo…