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10건 · 최신순-
Pediatric retrograde cricopharyngeal dysfunction diagnosed by high-resolution impedance manometry.
[OBJECTIVES] The inability to burp, known as retrograde cricopharyngeal dysfunction (R-CPD), was initially described in adults. The proposed clinical diagnostic criteria for R-CPD include belching inability, abdominal bloating and discomfor…
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Botulinum Toxin in the Management of Children with Cerebral Palsy.
During the past 25 years, botulinum toxin type A (BoNT-A) has become the most widely used medical intervention in children with cerebral palsy. In this review we consider the gaps in our knowledge in the use of BoNT-A and reasons why muscle…
- Authors' Reply to K. Langdon and Colleagues' Comment on: "Botulinum Toxin in the Management of Children with Cerebral Palsy".
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Surgical trauma induces overgrowth in lower limb gigantism: regulation with use of rapamycin is promising.
We describe an unclassified overgrowth syndrome characterised by unregulated growth of dermal fibroblasts in the lower limbs of a 35-year-old woman. A gene mutation resulted in lower limb gigantism. Below the waist, she weighed 117 kg with…
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Injection frequency of botulinum toxin A for spastic equinus: a randomized clinical trial.
[AIM] We compared two botulinum toxin A (BoNT-A) injection frequency regimens, 12-monthly versus 4-monthly, for spastic equinus in a randomized clinical trial. The primary outcome measure was passive ankle dorsiflexion. [METHOD] Forty-two …
- A full time regional ortho-plastic unit; initial results.
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Next generation sequencing profiling identifies miR-574-3p and miR-660-5p as potential novel prognostic markers for breast cancer.
[BACKGROUND] Prognostication of Breast Cancer (BC) relies largely on traditional clinical factors and biomarkers such as hormone or growth factor receptors. Due to their suboptimal specificities, it is challenging to accurately identify the…
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A 3-dimensional model for teaching local flaps using porcine skin.
The European Working Time Directive and streamlined training has led to reduced training time. Surgery, as an experience-dependent craft specialty is affected more than other medical specialties. Trainees want to maximize all training oppor…
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Gene expression in histologically normal epithelium from breast cancer patients and from cancer-free prophylactic mastectomy patients shares a similar profile.
[INTRODUCTION] We hypothesised that gene expression in histologically normal (HN) epithelium (NlEpi) would differ between breast cancer patients and usual-risk controls undergoing reduction mammoplasty (RM), and that gene expression in NlEp…
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Surgical interventions for the treatment of radiation-induced alopecia in pediatric practice.
Permanent alopecia can occur following treatment for pediatric malignant disease, especially cranial irradiation, resulting in identity and self-image problems. This late effect is usually addressed through external cosmesis and psychologic…