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Microvascular Free Tissue Transfer for Reconstruction of Anterior Skull Base Defects.
[BACKGROUND] We present our experience with free flap reconstruction of the anterior skull base (SB), focusing on complex composite defects in patients undergoing multimodality therapy for SB tumors. [METHODS] Outcomes of patients undergoi…
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Response-Adapted Oncologic Surgery in Cutaneous Squamous Cell Carcinoma: A Paradigm Shift Following Neoadjuvant Immunotherapy.
[BACKGROUND] Recent studies suggested that neoadjuvant cemiplimab can achieve a significant pathologic response in patients with cutaneous squamous cell carcinoma (CSCC). This was a retrospective cohort study (2018-2021) to determine whethe…
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The combined profunda artery perforator-gracilis flap for immediate facial reanimation and resurfacing of the radical parotidectomy defect.
[BACKGROUND] A radical parotidectomy with facial nerve sacrifice results in facial nerve paralysis as well as a volume and often cutaneous defect. Prior experience with nerve grafting and static suspension has yielded suboptimal results. Th…
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Surgical Management of Skull Base Osteoradionecrosis in the Cancer Population - Treatment Outcomes and Predictors of Recurrence: A Case Series.
[BACKGROUND] Skull base osteoradionecrosis (ORN) is a challenging treatment-related complication sometimes seen in patients with cancer. Although ORN management strategies for other anatomic sites have been reported, there is a paucity of d…