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15건 · 최신순-
Spiky Nanoparticle-Gel Composite for Efficient Intravesical Botulinum Toxin A Delivery and Treatment of Overactive Bladder.
Overactive bladder (OAB) is a symptomatic disease that is difficult to treat. This study developed APTES-functionalized spiky titanium dioxide nanoparticles (ASNPs) loaded with botulinum toxin A (ASNP@BA), which is coated with P407/HA (HP) …
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A modified second toe nail-skin flap for refined reconstruction of the distal index finger defect.
[BACKGROUND] The defect of the distal index finger may cause tissue necrosis, osteomyelitis, even dysfunction, disability in hand, and psychological problems. This study aimed to present our experiences using a modified second toe nail-skin…
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Infection of Anterolateral Thigh Free Flap With Multiple Digestive Tract Bacteria Involvement After Excision of Auricular Squamous Cell Carcinoma.
[OBJECTIVE] The authors present a case of an infected anterolateral thigh flap repairing the defect after auricular squamous cell carcinoma surgery. [METHODS] A 59-year-old male with squamous cell carcinoma in the right auricle was admitte…
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Advancements in the management of overactive bladder in women using nano-botulinum toxin type A: A narrative review.
Intravesical injections of botulinum toxin type A (BTX-A) are effective for treating refractory overactive bladder (OAB) in women. However, the adverse effects linked to the injections, such as hematuria, pain, and infection, and need for r…
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Safety and efficacy of intravesical instillation of botulinum toxin-A in the treatment of interstitial cystitis/bladder pain syndrome and overactive bladder: a systematic review and meta-analysis.
[BACKGROUND] The effectiveness and safety of the instillation of botulinum toxin A (BTX-A) remain subjects of controversy. The meta-analysis was performed to assess the efficacy and safety of a novel intravesical instillation of BTX-A for m…
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The Comparative Effectiveness of Botulinum Toxin-A Injection Therapy Versus Augmentation Uretero-Enterocystoplasty for the Treatment of Lower Urinary Tract Dysfunction.
[PURPOSE] We investigated the effectiveness of intravesical botulinum toxin-A (BTX-A) injection therapy in patients with lower urinary tract dysfunction (LUTD) and upper urinary tract (UUT) deterioration and evaluated whether BTX-A injectio…
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Augmentation Uretero-enterocystoplasty Is an Effective Procedure in Protecting the Upper Urinary Tract Without Accelerating Deterioration of Renal Function.
[BACKGROUND] Augmentation uretero-enterocystoplasty (AUEC) provides a low-pressure urinary storage capsule that can preserve renal function in patients with lower urinary tract dysfunction for whom conservative treatments have failed. [OBJ…
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Ultrasound-assisted intravesical botulinum toxin A delivery attenuates acetic acid-induced bladder hyperactivity in rats.
Intradetrusor injection of botulinum toxin A (BTX-A) is an effective treatment for overactive bladder (OAB). However, the occurrence of adverse events associated with BTX-A injection therapy hinders its acceptance among patients and its cli…
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Hengli Chinese Botulinum Toxin Type A for Treatment of Patients With Overactive Bladder: A Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.
To evaluate the efficacy and safety of Hengli Chinese botulinum toxin type A (BTX-A; 100 U) in Chinese patients with overactive bladder. This study was a multicenter, randomized, double-blind, placebo-controlled trial in Chinese patients w…
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Nano-BTA: A New Strategy for Intravesical Delivery of Botulinum Toxin A.
Botulinum neurotoxin subtype A (BoNT-A) has been part of the urology treatment arsenal since it was first used in the treatment of detrusor-sphincter dyssynergia more than 30 years ago. BoNT-A has been recommended as an effective treatment …
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Chinese botulinum toxin A for the treatment of lower urinary tract dysfunction: It works just as well.
The botulinum neurotoxin type A (BoNT/A) is a neurotoxin produced by . It causes botulism and represents the most powerful natural poison. In urological practice, the indications for BoNT/A therapy include neurogenic detrusor overactivity (…
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Identification of Type H Vessels in Mice Mandibular Condyle.
Type H vessel is a specific vessel subtype that is strongly positive for CD31 and endomucin (CD31Emcn). It has already been identified that it can tightly regulate the coupling of angiogenesis and osteogenesis in the long bone of mice and h…
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Efficacy and safety of botulinum toxin a injection into urethral sphincter for underactive bladder.
[BACKGROUND] The aim of this retrospective study was to evaluate the clinical efficacy and safety of botulinum toxin type A (BTX-A) injection into the urethral sphincter to treat patients with underactive bladder (UAB). [METHODS] From Sept…
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Intraoral Prosthetic Chin Augmentation With Vertical Incisions.
To explore a new surgical approach for chin augmentation using a prosthesis with 3 intraoral vertical incisions whereby placement of the prosthesis is more convenient and accurate, with fewer postoperative complications. Following the anato…
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Correction of asymmetric facial deformity by contouring: indications and outcomes.
[BACKGROUND] Facial asymmetry is usually due to unbalanced development of the lower jaw and zygoma and often results in esthetically unpleasant appearance. However, reasonable and systematic treatment of such an asymmetric face is rarely re…