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Carotid Blowout Syndrome in Head and Neck Cancer Patients after Free Flap Reconstruction.
Carotid blowout syndrome (CBS) is a rare but potentially fatal complication in head and neck cancer patients who have undergone free flap reconstruction and/or radiotherapy. This review examines CBS, with incidence ranging from 0.5-0.9% in …
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Airway Management Following Head and Neck Microvascular Reconstruction: When is a Tracheostomy Necessary?
Head and neck free flap reconstruction presents complex airway challenges due to postoperative swelling, bleeding, and anatomical distortion that can jeopardize breathing. Many centers once performed routine prophylactic tracheostomy for ma…
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Edge De-epithelialization for Reducing Pharyngocutaneous Fistula in Patch Free Flap Reconstructions for Salvage Total Laryngectomy Defects: A Case-Control Study.
[BACKGROUND] The leakage of saliva through the deep neck region from a pharyngocutaneous fistula could cause devastating complications, including vascular ruptures leading to mortality. While a partial pharyngoesophageal defect is created a…
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Risk factors associated with postoperative complications of free anterolateral thigh flap placement in patients with head and neck cancer: Analysis of propensity score-matched cohorts.
[BACKGROUND] From the perspective of a surgeon, knowledge of the operative risk factors that may affect postoperative outcomes is important in free anterolateral thigh (ALT) flap reconstruction for head and neck defects after tumor ablation…
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The Rho/Rac Guanine Nucleotide Exchange Factor Vav1 Regulates Hif-1α and Glut-1 Expression and Glucose Uptake in the Brain.
Vav1 is a Rho/Rac (Ras-related C3 botulinum toxin substrate) guanine nucleotide exchange factor expressed in hematopoietic and endothelial cells that are involved in a wide range of cellular functions. It is also stabilized under hypoxic co…