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Flat mount preparation for whole-mount fluorescent imaging of zebrafish embryos.
The zebrafish is a widely used model organism for biomedical research due to its ease of maintenance, external fertilization of embryos, rapid embryonic development, and availability of established genetic tools. One notable advantage of us…
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Noninvasive spinal neuromodulation mitigates symptoms of idiopathic overactive bladder.
[BACKGROUND] Overactive bladder (OAB) affects 12 to 30% of the world's population. The accompanying urinary urgency, frequency and incontinence can have a profound effect on quality of life, leading to depression, social isolation, avoidanc…
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A prospective study of intrapyloric botulinum toxin and EndoFLIP in children with nausea and vomiting.
[BACKGROUND] Intrapyloric botulinum toxin injection (IPBI) is used to treat nausea and vomiting in children, but no prospective pediatric studies exist. The aims of the current study were to assess the efficacy of IPBI in children with refr…
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Mechanism and Priority of Botulinum Neurotoxin A versus Sacral Neuromodulation for Refractory Overactive Bladder: A Review.
[BACKGROUND] The treatment of common overactive bladder (OAB) has reached a consensus, but there is not a clear answer to the treatment of refractory OAB (ROAB). ROAB is defined as nonresponsive to treatment with behavioural and oral therap…
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Sensitivity and specificity of the diagnosis of periocular lesions by oculoplastic surgeons.
[BACKGROUND] A few studies have assessed the sensitivity of ophthalmologists in diagnosing periocular lesions. However, no study has assessed their diagnostic specificity or the degree to which they overdiagnose various lesions. We performe…