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Use of Superficial Temporal Vessels in Reconstructive Oral and Maxillofacial Surgery With Vascularized Free Flaps Among "Frozen Neck" Patients.
[BACKGROUND] This study aimed to evaluate the feasibility of using superficial temporal vessels as recipient vessels for vascularized free flap reconstruction in "frozen neck" patients following radiotherapy for head and neck cancer (HNC). …
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An open source in silico workflow to assist in the design of fusion proteins.
Fusion proteins have the potential to become the new norm for targeted therapeutic treatments. Highly specific payload delivery can be achieved by combining custom targeting moieties, such as V domains, with active parts of proteins that ha…
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Use of free flaps with supermicrosurgery for oncological reconstruction of the maxillofacial region.
Supermicrosurgery involves the dissection and anastomosis of vessels…
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Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2 DRG sensory neurons.
Bacterial products can act on neurons to alter signaling and function. In the present study, we found that dorsal root ganglion (DRG) sensory neurons are enriched for ANTXR2, the high-affinity receptor for anthrax toxins. Anthrax toxins are…