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High-Throughput Biofilm Assay to Investigate Bacterial Interactions with Surface Topographies.
The specific topography of biomaterials plays an important role in their biological interactions with cells and thus the safety of medical implants. Antifouling materials can be engineered with topographic features to repel microbes. Meanwh…
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Putative mechanobiological impact of surface texture on cell activity around soft-tissue implants undergoing micromotion.
Recent reports of adverse health effects (e.g., capsular contracture, lymphoma) linked to the absence or presence of texture on soft-tissue implants (e.g., breast implants) suggest surface topography may have pathological impact(s). We prop…
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In vitro and in vivo methods to study bacterial colonization of hydrogel dermal fillers.
Preclinical in vitro and in vivo methods to study bacterial interactions with dermal fillers and infection pathogenesis are lacking. In this work, first in vitro methods to assess protein biofouling and effective pore size of commercial der…
- U.S. Food and Drug Administration Authors Publish Articles on Dermal Filler Materials, Injections, Methods, and Skin Preparation.