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Pre-proenkephalin 1 is Downregulated Under Unloading and is Involved in Osteoblast Biology.
Pre-proenkephalin 1 (Penk1) is a pro-neuropeptide that belongs to the typical opioid peptide's family, having analgesic properties. We previously found Penk1 to be the most downregulated gene in a whole gene profiling analysis performed in …