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Recent Developments in Botulinum Neurotoxins Detection.
Botulinum neurotoxins (BoNTs) are produced as protein complexes by bacteria of the genus that are Gram-positive, anaerobic and spore forming (, , and spp.). BoNTs show a high immunological and genetic diversity. Therefore, fast, precise,…
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In Silico Conformational Features of Botulinum Toxins A1 and E1 According to Intraluminal Acidification.
Although botulinum neurotoxins (BoNTs) are among the most toxic compounds found in nature, their molecular mechanism of action is far from being elucidated. A key event is the conformational transition due to acidification of the interior o…