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3건 · 최신순-
Intramuscular injection of therapeutic botulinum toxin facilitates blood coagulation in experimental aging mice.
[BACKGROUND] Botulinum toxin (BoNT) is a bacterial poison that acts by blocking the release of acetylcholine-containing vesicles at the neuromuscular junction. Notably, a mild amount of BoNT is known to exert therapeutic benefits against va…
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Single injection of very mild dose botulinum toxin in the vastus lateralis improves testicular spermatogenesis and sperm motility in ageing experimental mice.
[BACKGROUND] Botulinum toxin (BoNT) is a widely used therapeutic agent that blocks the excessive release of acetylcholine at the neuromuscular junction. Previously, repeated intracremasteric injections and slight overdose of BoNT have been …
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BOTOX® counteracts the innate anxiety-related behaviours in correlation with increased activities of key antioxidant enzymes in the hippocampus of ageing experimental mice.
Cholinergic crisis and oxidative stress in the hippocampus of the brain have been known to induce anxiety disorders upon ageing. BOTOX® is a widely used therapeutic form of botulinum neurotoxin that acts by inhibiting the release of acetylc…