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3건 · 최신순-
Quantitative determination of estrone by liquid chromatography-tandem mass spectrometry in subcutaneous adipose tissue from the breast in postmenopausal women.
Estrone is the most abundant estrogen after the menopause. We developed a liquid chromatography-tandem mass spectrometric method (LC-MS/MS) for determination of estrone in adipose tissue. Subcutaneous adipose tissue from the breast was coll…
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Breast adipose tissue estrogen metabolism in postmenopausal women with or without breast cancer.
[CONTEXT] It has been shown that breast tumor actively produces and metabolizes steroid hormones. However, little is known about the possible mechanisms through which the nonmalignant adipose tissue contributes to steroid hormone metabolism…
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Fatty acyl esterification and deesterification of 17β-estradiol in human breast subcutaneous adipose tissue.
[CONTEXT] Adipose tissue has an important role in peripheral estrogen synthesis. One of the metabolic pathways of estradiol (E(2)) is its conversion to lipophilic fatty acyl esters. [OBJECTIVE] The aim was to study the metabolism of E(2) f…