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Genomic (in)stability of the breast tumor microenvironment.
The breast tumor microenvironment plays an active role in tumorigenesis. Molecular alterations have been identified in tumor-associated stroma; however, there is considerable debate as to whether the stroma is characterized by genomic insta…
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The Clinical Breast Care Project: an important resource in investigating environmental and genetic contributions to breast cancer in African American women.
Age at diagnosis, pathological characteristics, and tumor behavior differ between African American (AAW) and Caucasian women (CW) with breast cancer, with AAW having more aggressive tumors and higher mortality rates. Although both societal …