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Impact of Prepectoral Implant Placement and Radiation Modalities (Protons/Photons/Dosimetry) in Mastectomy Patients Undergoing Immediate Single Stage Direct-to-Implant Breast Reconstruction.
[PURPOSE] For patients with breast cancer receiving mastectomy with direct-to-implant (DTI) immediate breast reconstruction, placing the implant in the prepectoral or subpectoral plane remains debatable, especially in settings of postmastec…
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Risk of Developing Breast Reconstruction Complications: A Machine-Learning Nomogram for Individualized Risk Estimation with and without Postmastectomy Radiation Therapy.
[BACKGROUND] The purpose of this study was to create a nomogram using machine learning models predicting risk of breast reconstruction complications with or without postmastectomy radiation therapy. [METHODS] Between 1997 and 2017, 1617 br…
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Postmastectomy Radiation Therapy on Permanent Implants or Tissue Expanders: Which is Better?
[OBJECTIVES] This study evaluates complications and reconstructive failure rates in implant-based reconstruction with radiotherapy. [BACKGROUND] Postmastectomy radiotherapy may adversely affect breast reconstructive outcomes. However, the …
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The Impact of Chest Wall Boost on Reconstruction Complications and Local Control in Patients Treated for Breast Cancer.
[PURPOSE] Giving an additional radiation dose to the incision or chest wall has been a practice, but it has never been studied in a randomized setting, and it might lead to inferior cosmetic outcomes. This study aims to evaluate whether del…
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Pathologic findings in reduction mammoplasty specimens: a surrogate for the population prevalence of breast cancer and high-risk lesions.
[PURPOSE] Mammoplasty removes random samples of breast tissue from asymptomatic women providing a unique method for evaluating background prevalence of breast pathology in normal population. Our goal was to identify the rate of atypical bre…
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Incidental breast carcinoma: incidence, management, and outcomes in 4804 bilateral reduction mammoplasties.
[INTRODUCTION] Bilateral reduction mammoplasty is one of the most common plastic surgery procedures performed in the U.S. This study examines the incidence, management, and prognosis of incidental breast cancer identified in reduction speci…
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Breast reconstruction outcomes after nipple-sparing mastectomy and radiation therapy.
[BACKGROUND] Few studies in the literature examine outcomes of immediate breast reconstruction after mastectomy with nipple preservation and radiation therapy. [METHODS] Retrospective analysis of multisurgeon consecutive implant-based reco…
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Nipple-sparing mastectomy in patients with previous breast surgery: comparative analysis of 775 immediate breast reconstructions.
[BACKGROUND] An increasing number of women are candidates for nipple preservation with mastectomy. It is unclear how previous breast surgery impacts nipple-sparing mastectomy and immediate breast reconstruction. [METHODS] A single-institut…