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The Second of Two One-Year, Multicenter, Open-Label, Repeat-Dose, Phase II Safety Studies of PrabotulinumtoxinA for the Treatment of Moderate to Severe Glabellar Lines in Adult Patients.
[BACKGROUND] PrabotulinumtoxinA is a 900-kDa botulinum toxin type A produced by Clostridium botulinum. [OBJECTIVES] The authors sought to investigate the safety of prabotulinumtoxinA for treatment of glabellar lines. [METHODS] This was a …
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Five-Year Safety and Satisfaction Study of PMMA-Collagen in the Correction of Nasolabial Folds.
[BACKGROUND] A polymethylmethacrylate-collagen filler is generally believed to give long-term benefits, but the risk of granuloma formation over time remains unclear. [OBJECTIVE] To determine the incidence of granuloma formation and respon…
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A double-blind, randomized, multicenter, controlled trial of suspended polymethylmethacrylate microspheres for the correction of atrophic facial acne scars.
[BACKGROUND] Acne scarring remains a stubborn clinical problem. Few treatments have been shown to be definitely effective for this problem. Polymethylmethacrylate (PMMA) microspheres in collagen (ArteFill, Suneva Medical Inc, Santa Barbara,…
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Effectiveness of Juvéderm Ultra Plus dermal filler in the treatment of severe nasolabial folds.
[BACKGROUND] With the baby boomer generation firmly ensconced in middle age and the ubiquity of botulinum toxin type A, nonsurgical facial rejuvenation is becoming increasingly prevalent. As this generation continues to age, products with g…
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Twelve-month persistency of a novel ribose-cross-linked collagen dermal filler.
[BACKGROUND] The porcine collagen-derived dermal filler Dermicol-P35 (Evolence, Colbar LifeScience Ltd, Herzliya, Israel) has low immunogenicity and the potential to provide a long-lasting corrective response for soft-tissue contour deficie…