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Epidemiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma - A systematic review of literature.
[INTRODUCTION] Breast Implant Associated - Anaplastic Large Cell Lymphoma (BIA-ALCL) cases are steadily increasing worldwide. When considering only the patients with textured implant as the active population, prevalence appears higher than …
- Estimating the Prevalence of Breast Implant-Associated Anaplastic Large-Cell Lymphoma: A Systematic Review.
- Response to: Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL): Comparison of Manufacturers From UK National Data.
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Quantifying Silicone Leakage In Vivo: Validation of a Reproducible Histological Method for Breast Implant Surveillance.
[BACKGROUND] Silicone leakage from breast implants may contribute to fibrosis leading to capsular contracture, yet no standardized method exists to quantify silicone leakage reliably. [OBJECTIVES] To validate a histological method for quan…
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The impact of Breast Implant-Associated Anaplastic Large Cell Lymphoma on breast implant surgery: A European survey-based study.
[BACKGROUND] Over the 27 years following the first report of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL), significant changes have been made in breast implant surgery trends. This study aimed to determine breast impl…
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Metaplastic carcinoma of the breast mimicking breast implant-associated squamous cell carcinoma: a challenging differential diagnosis.
Metaplastic carcinoma of the breast (MBC) is an uncommon disease that accounts for 0.2-1% of all invasive breast carcinomas, comprising a heterogeneous group of diseases characterized by differentiation of the neoplastic epithelium to squam…
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Limitations of Estimating BIA-ALCL Incidence Risk Using Implant Sales Data and the Italian National Breast Implant Registry.
Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors …
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Behind the Title, Nothing! Reply to: "The (In-)Ability to Effectively Critique a Method Undermines the Validity of the Criticism".
Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors …
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2024 EURAPS Expert Consensus on breast implant associated-anaplastic large cell lymphoma.
[BACKGROUND] Despite nearly three decades of investigation since its initial report, breast implant associated-anaplastic large cell lymphoma (BIA-ALCL) remains an elusive and evolving clinical entity. [OBJECTIVES] This manuscript presents…
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High-Throughput Molecular Characterization of the Microbiome in Breast Implant-Associated Anaplastic Large Cell Lymphoma and Peri-Implant Benign Seromas.
: Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a mature T-cell lymphoma linked to textured breast implants. A leading hypothesis suggests that chronic inflammation, combined with immunological and genetic factors, …
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Inflammatory response to various implant surfaces in murine models: A systematic analysis.
Breast implants (BIs) are commonly used in cosmetic and reconstructive breast surgery but are linked to several complications such as capsular contracture, implant rupture, and potential malignancies. The key to mitigating these issues is t…
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Effect of Different Medications on Capsule Formation Around Miniaturized Breast Implants in Murine Models-a Systematic Review.
[BACKGROUND] Breast implants (BIs) lead to the formation of a periprosthetic capsule, causing complications like capsular contracture. Gel bleeding, involving minor silicone gel leakage through the intact implant shell, significantly promot…
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Microsurgical reconstruction of the heel: evaluation and decision-making recommendations based on a case series.
Reconstruction of the calcaneal region presents unique challenges due to its complex anatomy and critical weight-bearing function. This retrospective study aims to report our experience in cases of calcaneal defects repaired with various fr…
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Secondary intact capsulectomy with seroma without implant: revision of an incomplete treatment of BIA-ALCL - a case report.
[BACKGROUND] Breast Implant Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) is a haematological malignancy which may occur in patients with textured breast implant history. While typically diagnosed at an early stage with good prognosi…
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Breast Implants and the Risk of Squamous Cell Carcinoma of the Breast: A Systematic Literature Review and Epidemiologic Study.
Squamous cell carcinoma may arise primarily from the breast parenchyma (PSCCB) or from the periprosthetic capsule in patients with breast implants (breast implant-associated squamous cell carcinoma [BIA-SCC]). A systematic literature review…
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Breast implant-associated anaplastic large cell lymphoma in Romania: First case series of all documented cases.
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), an uncommon malignancy, was linked to textured breast implants by moderate evidence in 2021. Documenting Romanian cases provides valuable insights into the epidemiology, m…
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DIEP flap perfusion assessment using microdialysis versus Doppler ultrasonography: A comparative study.
[BACKGROUND] The increasing number of buried free-tissue transfer procedures and the need for an objective method to evaluate vascular complications of free flaps has led to the development of new technologies. Microdialysis has been used t…
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Snip conjunctivoplasty associated with methylene blue staining for treatment of postoperative conjunctival chemosis.
Conjunctival chemosis usually undergoes spontaneous resolution; sometimes, it requires treatment. We present the case of a 43 years-old female patient who developed bilateral conjunctival chemosis following upper and lower blepharoplasty. T…
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BIA-ALCL Epidemiological Findings From a Retrospective Study of 248 Cases Extracted From Relevant Case Reports and Series: A Systematic Review.
[BACKGROUND] The epidemiologic picture of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is unclear, with no high-level evidence, because only case reports and series are available. [OBJECTIVES] The aim of this study w…
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Epidemiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma in the United States: A Systematic Review.
[BACKGROUND] Although textured implants represent fewer than 10% of implants used in the United States, the country reports the highest incidence of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). [OBJECTIVES] The aim …
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Comment on the Invited Discussion on "Assessment of Risk Factors for Rupture in Breast Reconstruction Patients with Macrotextured Breast Implants".
We here present a few comments on the invited discussion of Dr. van Heijningen on the paper "Assessment of Risk Factors for Rupture in Breast Reconstruction Patients with Macrotextured Breast Implants". Dr. van Heijningen made some reservat…
- The Superficial Vein-Only DIEP Flap.
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Free-style technique versus computed tomographic angiography-guided perforator selection in deep inferior epigastric perforator flap harvest: A prospective clinical study.
[BACKGROUND] Computed tomographic angiography (CTA) is the preferred diagnostic tool in preoperative deep inferior epigastric perforator (DIEP) flap assessment, though some surgeons prefer approaching perforator selection with intraoperativ…
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Effects of DIEP flap-based breast reconstruction on respiratory function.
[BACKGROUND] Breast reconstruction (BR) is an essential part of breast cancer treatment, and the DIEP flap is considered the gold standard reconstruction technique, which uses a free abdominal flap. Concerns have been raised regarding the e…
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Mortality Rate in Breast Implant Surgery: Is an Additional Procedure Worthwhile to Mitigate BIA-ALCL Risk?
[BACKGROUND] Because of poor knowledge of risks and benefits, prophylactic explantation of high BIA-ALCL risk breast implant (BI) is not indicated. Several surgical risks have been associated with BI surgery, with mortality being the most f…
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BIA-ALCL Epidemiology in an Aesthetic Breast Surgery Cohort of 1501 Patients.
[BACKGROUND] Epidemiologic studies on breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) currently estimate the risk between 1:300 and 1:30,000, assessed mainly in large breast reconstruction populations. [OBJECTIVES] The …
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Successful Treatment of a Patient With Breast Implant-Associated Anaplastic Large Cell Lymphoma With Local Residual Disease: A Case Report.
[BACKGROUND] Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a hematological malignancy that may occur in patients undergoing breast implant placement. It more commonly behaves as a solid tumor, and the criterion stan…
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2022 Practice Recommendation Updates From the World Consensus Conference on BIA-ALCL.
[BACKGROUND] Laboratory and clinical research on breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is rapidly evolving. Changes in standard of care and insights into best practice were recently presented at the 3rd World C…
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History of breast implants: Back to the future.
Modern breast implants are a staple of plastic surgery, finding uses in esthetic and reconstructive procedures. Their history began in the 1960s, with the first generation of smooth devices with thick silicone elastomer, thick silicone gel,…
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A multicentre study of the relationship between abdominal flap and mastectomy weights in immediate unilateral free flap breast reconstruction and the effect of adjuvant radiotherapy.
Abdominal free flaps are considered the gold standard for post-mastectomy autologous breast reconstruction. A key element of outcome assessment is breast symmetry often achieved by approximating the reconstructed breast dimensions such as w…