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MiR-539-3p inhibited chondrogenic differentiation in human adipose stem cells by targeting Sox9.
[BACKGROUND] Mesenchymal stem cells (MSCs) have emerged as the attractive candidates for cell therapy for cartilage repair in clinical therapy of osteoarthritis (OA). MiR-539-3p was reported to differentially express during chondrogenic dif…
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Freezing of Gait in Parkinsonism and its Potential Drug Treatment.
Freezing of gait (FOG) is a heterogeneous symptom. Studies of treatment for FOG are scarce. Levodopa and monoamine oxidase inhibitors (rasagiline and selegiline) have shown effective improvement for FOG. Other drugs, such as L-threo-3, 4-di…