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8건 · 최신순-
[Comparison of the effects of continuous infusion of two doses of mivacurium in laryngeal microsurgery].
To compare the neuromuscular blocking effects and postoperative recovery profiles of continuous infusion of two doses of mivacurium during laryngeal microsurgery. From October to December 2022, 62 patients scheduled for elective laryngeal …
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Botulinum Toxin Type A Inhibits Submandibular Secretion via the ERK/miR-124-3p/Specificity Protein 1/Claudin-1 Axis.
Botulinum toxin type A (BTXA) is widely used for the treatment of sialorrhea; however, its mechanism remains unclear. Tight junctions (TJs) are limiting factors for salivary secretion through the paracellular pathway in the salivary gland, …
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Alteration of tight junctions during botulinum toxin type A-inhibited salivary secretion.
[OBJECTIVES] Tight junctions (TJs) are involved in the regulation of salivary secretion via paracellular pathway. Botulinum toxin type A (BTXA) is widely used for the treatment of hypersecretion diseases such as sialorrhea. This study aimed…
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[Comparison of the anesthetic effects of mivacurium and cisatracurium besylate in laser laryngeal microsurgery].
To compare the anesthetic effects of mivacurium and cisatracurium besylate in laser laryngeal microsurgery, and to provide clinical evidence and reference for further optimization of muscle relaxation application. From October 2021 to Janu…
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Aberrantly expressed lncRNAs and mRNAs after botulinum toxin type A inhibiting salivary secretion.
[OBJECTIVE] In this study, we sought to determine the expression profiles of long non-coding RNAs (lncRNAs) and messenger RNAs (mRNAs) and construct functional networks to analyze their potential roles following botulinum toxin type A (BTXA…
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MicroRNA-mRNA expression profiles and functional network after injection of botulinum toxin type A into submandibular glands.
Botulinum toxin type A (BTXA) is effective for the treatment of sialorrhea. MicroRNAs (miRNAs) have significant functions in salivary diseases, but the role of miRNAs during BTXA-inhibited salivary secretion is not yet clear. A total of 19 …
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[Role and mechanism of muscarinic acetylcholine receptor in the regulation of submandibular gland secretion].
Muscarinic acetylcholine receptors (mAChRs), including M1-M5 subtypes, are classic receptors in regulating water, ion, and solute transport in salivary gland. Our work focuses on the studies on the expression pattern and function of mAChR i…
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Pre- and Post-synaptic Effects of Botulinum Toxin A on Submandibular Glands.
Intraglandular injection of botulinum toxin type A (BoNT/A) is an effective treatment for sialorrhea. Despite numerous experimental and clinical studies on inhibition of saliva section by BoNT/A, the proteolysis of synaptosomal-associated p…