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Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway.
Exposure of articular cartilage to excessive mechanical loading is deeply involved in the pathogenesis of osteoarthritis. Here, we identify gremlin-1 as a mechanical loading-inducible factor in chondrocytes, detected at high levels in middl…
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Data analyses and perspectives on laparoscopic surgery for esophageal achalasia.
In general, the treatment methods for esophageal achalasia are largely classified into four groups, including drug therapy using nitrite or a calcium channel blocker, botulinum toxin injection, endoscopic therapy such as endoscopic balloon …