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10건 · 최신순-
Developing a predictive nomogram model for incidence of adverse outcomes in oral and maxillofacial tumor patients undergoing free flap reconstruction.
[BACKGROUND] Surgical treatment of oral and maxillofacial tumors is complex, and the factors contributing to adverse outcomes remain incompletely understood. This study aimed to identify independent risk factors and develop an efficient nom…
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Successful Treatment of Complex and Refractory Rosacea Using Platelet-Rich Plasma Injection Therapy: Case Series and Review of the Literature.
[BACKGROUND] Rosacea is a chronic inflammatory skin disease that affects a notable proportion of the adult population. Platelet-rich plasma (PRP) has been widely used to treat various inflammatory diseases due to its potent anti-inflammator…
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Botulinum Toxin Type A Alleviates Androgenetic Alopecia by Inhibiting Apoptosis of Dermal Papilla Cells via Targeting circ_0135062/miR-506-3p/Bax Axis.
Botulinum toxin type A (BTXA) has the potential to treat androgenetic alopecia (AGA); however, its impact on the apoptosis of dermal papillary cells (DPCs) is not yet fully understood. Noncoding RNAs play a crucial role in AGA. In this stud…
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Regulated extravascular microenvironment reversible thermosensitive hydrogel for inhibiting calcium influx and vasospasm.
Arterial vasospasm after microsurgery can cause severe obstruction of blood flow manifested as low tissue temperature, leading to tissue necrosis. The timely discovery and synchronized treatment become pivotal. In this study, a reversible, …
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Pharmacovigilance-based drug repurposing: searching for putative drugs with hypohidrosis or anhidrosis adverse events for use against hyperhidrosis.
[BACKGROUND] Drug repurposing refers to the application of existing drugs to new therapeutic indications. As phenotypic indicators of human drug response, drug side effects may provide direct signals and unique opportunities for drug repurp…
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Fat Compartment Gliding Theory - A Novel Technique for the Repositioning of Superficial Fat Compartments for Facial Rejuvenation.
[BACKGROUND] Facial fat compartments and their role in facial aging have gained increased recognition and are playing a significant role in facial rejuvenation. The superficial fat compartments glide inferiorly during the aging process, lea…
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Comparison of Botulinum toxin type A with surgery for the treatment of intermittent exotropia in children.
[BACKGROUND] The aim of this study was to observe the effectiveness of botulinum toxin type A (BTA) in the treatment of intermittent exotropia (IXT) in children compared with strabismus surgery. [METHODS] One hundred forty-four children wi…
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RAC3 Inhibition Induces Autophagy to Impair Metastasis in Bladder Cancer Cells the PI3K/AKT/mTOR Pathway.
[BACKGROUND] Bladder cancer (BCa) is one of the most frequent malignant tumors globally, with a significant morbidity and mortality rate. Gene expression dysregulation has been proven to play a critical role in tumorigenesis. Ras-related C3…
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Dropped head syndrome: a rare adverse drug reaction identified in the FDA adverse event reporting system and review of case reports in the literature.
[BACKGROUND] Dropped head syndrome (DHS) is a relatively rare disease, and its potential relationship with drug exposure has been postulated but is poorly understood. [RESEARCH DESIGN AND METHODS] This retrospective study evaluated the adv…
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Microsurgery vs. Gamma Knife Radiosurgery for the Treatment of Brainstem Cavernous Malformations: A Systematic Review and Meta-Analysis.
Brainstem cavernous malformations (BSCMs) are a subset of cerebral cavernous malformations with precarious locations and potentially devastating clinical courses. The effects and outcomes of treating BSCMs by microsurgery or gamma knife rad…