폴리락트산 Polylactic Acid (PLLA)

Current injectable fillers often suffer from a transient efficacy and insufficient early stage improvement. To address this, we developed a composite dermal filler consisting of hyaluronic acid (HA) and poly-L-lactic acid-methoxypolyethylen…

Mandibular continuity defects following tumor resection or trauma present significant reconstructive challenges, particularly for subsequent dental rehabilitation. While the fibula free flap remains the gold standard, its limited vertical h…

[PURPOSE] The use of cosmetic fillers has become increasingly popular. Radiologists and sonographers should be aware of the ultrasonographic characteristics of the most commonly used cosmetic fillers and the sonographic features of their fr…

[INTRODUCTION] Autologous fat grafting remains a topic of debate, involving not only the pathophysiology of its absorption but also the techniques that promote better integration for more predictable results. [OBJECTIVE] This study aimed t…

[BACKGROUND] Facelift surgery is a cornerstone of facial rejuvenation, yet it may not fully address volume loss, skin quality, or other age-related changes. Minimally invasive procedures-such as injectables and energy-based devices-are incr…

[BACKGROUND] Facial rejuvenation involves addressing the breakdown of collagen and elastin that occurs with aging. Hyaluronic acid (HA)-based dermal fillers have become a key non-invasive treatment, known for their volumizing effects and po…

Acne vulgaris is a highly prevalent chronic inflammatory disorder that frequently results in permanent scarring, with atrophic scars representing the predominant type. The management of atrophic acne scarring is challenging due to variabili…

[INTRODUCTION] Polylactic acid can be classified into poly(L-lactic acid) (PLLA) and poly(D,L-lactic acid) (PDLLA) according to their stereoisomeric structures, and both are widely used as dermal fillers for soft tissue augmentation. Althou…

[BACKGROUND] Delayed inflammatory and fibrotic reactions to dermal fillers remain unpredictable, reflecting complex interactions between product composition and host genetics. [OBJECTIVE] To develop and validate a computational framework i…

[BACKGROUND] It is unknown whether facial injectable treatments before rhytidectomy increase the risk of surgical complications, and data on the safety of rhytidectomy after prior injectable (PI) treatments are essential for clinicians and …

The chin and prejowl areas play a critical role in the perception of facial harmony. This paper explores nonsurgical approaches for chin and prejowl rejuvenation, emphasizing anatomy, aesthetic concerns, and the plethora of available treatm…

Neurotoxins and fillers have become increasingly popular for restoring age-related changes in the perioral region. This review examines their roles in optimizing perioral rejuvenation.The perioral region composes the lower third and middle …

Vascular complications after facial filling with hyaluronic acid/poly-l-lactic acid (HA/PLLA) composite fillers are rare. Herein, the authors report a case of vascular occlusion after nose and nasolabial fold augmentation with HA/PLLA that …

[BACKGROUND] Device-assisted drug delivery (DADD) involves a device modality that facilitates the penetration of topical substances across the intact stratum corneum barrier. [OBJECTIVE] This study analyzes the efficacy of a novel pneumati…

[BACKGROUND] Intradermal injections of fillers such as poly-L-lactic acid (PLLA) microspheres and hyaluronic acid (HA) offer the possibility of skin rejuvenation. However, the biological effects of these fillers and the mechanisms underlyin…

Vascular anastomosis is the cornerstone in microsurgery. To assist complicated microvascular anastomosis with diameters …

Breast thread lifting is a minimally invasive technique for correcting mild to moderate ptosis, offering aesthetic enhancement with reduced morbidity compared to traditional mastopexy. This review examines the anatomical underpinnings, clin…

[INTRODUCTION] Aesthetic medicine has evolved towards minimally invasive procedures, with biostimulators like Poly-L-Lactic Acid (PLLA), Calcium Hydroxylapatite (CaHA), and Polycaprolactone (PCL) gaining attention for their role in collagen…

Recently, various biocompatible and biodegradable materials have garnered significant attention as cosmetic fillers for skin rejuvenation. Among these, poly ε-caprolactone (PCL), poly L-lactic acid (PLLA), poly D,L-lactic acid (PDLLA), and …

[BACKGROUND] The nose, eyebrow, and forehead are critical elements of the T-zone, vital for enhancing facial three-dimensionality. Many Asians seek a more contoured and sculpted facial appearance by T-zone augmentation. The novel poly-L-lac…