[Diagnosis and treatment of osteogenic sarcomas, techniques of reconstructions. Future prospects].
Abstract
[PATIENTS AND METHODS] We have performed 34 massive bone-cartilage grafts with a follow-up of 2 to 7 years (1988-1993) including 5 complete joint grafts of the knee. Between 1988 and 1993, 8 massive diaphyso-metaphyseal bone grafts were performed. Joint reconstructions using massive bone-cartilage allografts are increasingly used in routine oncology surgery. Long-term rehabilitation and possibilities of immediate anatomic reconstruction of the articular surface, together with mid-term results suggest that the functional results are promising compared with major reconstruction prostheses. Indications for operations are being increasingly widened to younger subjects who have undergone partial or total joint exeresis for tumour. Sleeved prostheses were used for 12 reconstructions (1988-1993) for sarcoma of the knee. RESULTS The risk of sepsis are comparable for the different groups and are mainly related to the quality of the skin repair during chemotherapy. Fractures of the graft occur when the fixation is insufficient or when rehabilitation exercises were too aggressive. Non-consolidation was exceptional when the junction between the allograft and the receiver bone is not surrounded with autologous spongious autografts. Joint instability and arthrosis depend on the stability of the ligament reconstruction. To this day, no Charcot type joint disease has been demonstrated, periarticular innervation has maintained joint trophism.
[DISCUSSION] There are still some incompletely resolved problems concerning the revascularization of the graft, its integration into the skeleton, the outcome of the grafted cartilage and that of the ligament formations attached to the graft or used as allografts. These massive grafts must be studied over a longer period of time but the early results are encouraging. Sleeved grafts using bone-bank specimens could be an intermediary solution which appears to be indicated in cases where the tumoural resection was particularly large removing bone, cartilage, ligaments and muscles. With these sleeved prostheses, the muscles can be refixed onto the graft thus reducing the risk of shank fracture and loosening. The use of a tibial graft with the patellar tendon is helpful in reconstructing the extensor apparatus. However, if rehabilitation is not undertaken rapidly and followed regularly for several months, the graft favours the development of muscular adherances which can be a major limitation to joint mobility.
[DISCUSSION] There are still some incompletely resolved problems concerning the revascularization of the graft, its integration into the skeleton, the outcome of the grafted cartilage and that of the ligament formations attached to the graft or used as allografts. These massive grafts must be studied over a longer period of time but the early results are encouraging. Sleeved grafts using bone-bank specimens could be an intermediary solution which appears to be indicated in cases where the tumoural resection was particularly large removing bone, cartilage, ligaments and muscles. With these sleeved prostheses, the muscles can be refixed onto the graft thus reducing the risk of shank fracture and loosening. The use of a tibial graft with the patellar tendon is helpful in reconstructing the extensor apparatus. However, if rehabilitation is not undertaken rapidly and followed regularly for several months, the graft favours the development of muscular adherances which can be a major limitation to joint mobility.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 해부 | bone-cartilage grafts
|
scispacy | 1 | ||
| 해부 | joint grafts
|
scispacy | 1 | ||
| 해부 | knee
|
scispacy | 1 | ||
| 해부 | bone-cartilage allografts
|
scispacy | 1 | ||
| 해부 | articular surface
|
scispacy | 1 | ||
| 해부 | skin
|
scispacy | 1 | ||
| 해부 | graft
|
scispacy | 1 | ||
| 해부 | bone
|
scispacy | 1 | ||
| 해부 | spongious autografts
|
scispacy | 1 | ||
| 해부 | ligament
|
scispacy | 1 | ||
| 해부 | cartilage
|
scispacy | 1 | ||
| 해부 | allografts
|
scispacy | 1 | ||
| 해부 | grafts
|
scispacy | 1 | ||
| 해부 | tumoural
|
scispacy | 1 | ||
| 해부 | ligaments
|
scispacy | 1 | ||
| 해부 | muscles
|
scispacy | 1 | ||
| 해부 | extensor
|
scispacy | 1 | ||
| 해부 | muscular
|
scispacy | 1 | ||
| 합병증 | shank fracture
|
scispacy | 1 | ||
| 합병증 | patellar tendon
|
scispacy | 1 | ||
| 질환 | sarcomas
|
C1261473
Sarcoma
|
scispacy | 1 | |
| 질환 | tumour
|
C0027651
Neoplasms
|
scispacy | 1 | |
| 질환 | sarcoma
|
C1261473
Sarcoma
|
scispacy | 1 | |
| 질환 | sepsis
|
C0036690
Septicemia
|
scispacy | 1 | |
| 질환 | Fractures of the graft
|
scispacy | 1 | ||
| 질환 | arthrosis
|
C0022408
Arthropathy
|
scispacy | 1 | |
| 질환 | Charcot
|
scispacy | 1 | ||
| 질환 | type joint disease
|
C0022408
Arthropathy
|
scispacy | 1 | |
| 질환 | periarticular innervation
|
scispacy | 1 | ||
| 질환 | fracture
|
C0016658
Fracture
|
scispacy | 1 | |
| 질환 | allograft
|
scispacy | 1 | ||
| 질환 | bone-bank specimens
|
scispacy | 1 | ||
| 기타 | diaphyso-metaphyseal bone grafts
|
scispacy | 1 | ||
| 기타 | Joint
|
scispacy | 1 | ||
| 기타 | periarticular
|
scispacy | 1 |
MeSH Terms
Adolescent; Adult; Bone Neoplasms; Bone Transplantation; Cartilage, Articular; Female; Follow-Up Studies; Humans; Male; Orthopedic Fixation Devices; Osteosarcoma; Surgery, Plastic