Skull expansion in experimental craniosynostosis.

Plastic and reconstructive surgery 1986 Vol.78(5) p. 594-603

Persing JA, Babler WJ, Nagorsky MJ, Edgerton MT, Jane JA

Abstract

Bilateral coronal suture immobilization was performed in 9-day-old rabbits to simulate the brachycephaly deformity characteristic of coronal synostosis. Growth abnormalities were documented by serial radiographic cephalometry. A "corrective" linear craniectomy procedure was performed on the rabbits with an immobilized coronal suture at 60 days of age. The degree of amelioration of the induced abnormalities by the surgery in these animals was compared with a similar group of animals that had the same surgery plus supplemental implantation of a spring expansion device at the coronal suture craniectomy site. The mean marker separation at the coronal suture was significantly greater (5.61 mm +/- 0.52 SE versus 2.53 mm +/- 0.38 SE; p less than 0.05) following spring expander implantation than with linear craniectomy alone. Similarly, induced anterior cranial base shortening and distortion of craniofacial cephalometrics were more significantly improved by the additional use of the spring expansion device.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 Skull scispacy 1
해부 craniofacial scispacy 1
합병증 brachycephaly scispacy 1
질환 craniosynostosis C0010278
Craniosynostosis
scispacy 1
질환 brachycephaly deformity scispacy 1
질환 coronal synostosis C4280330
Coronal synostosis
scispacy 1
질환 distortion of craniofacial cephalometrics scispacy 1
기타 9-day-old rabbits scispacy 1
기타 rabbits scispacy 1
기타 anterior cranial scispacy 1

MeSH Terms

Animals; Animals, Newborn; Cephalometry; Cranial Sutures; Craniosynostoses; Craniotomy; Prostheses and Implants; Rabbits; Radiography; Skull; Statistics as Topic; Surgery, Plastic