Adjunct hyperbaric oxygen therapy in periorbital reconstruction.

Archives of ophthalmology (Chicago, Ill. : 1960) 1986 Vol.104(3) p. 439-43

Gonnering RS, Kindwall EP, Goldmann RW

Abstract

The abundant blood supply normally found in the periorbital region grants the reconstructive surgeon many options for repair. When this blood supply is altered by such factors as thermal damage or scar formation, classic methods of lid reconstruction may not suffice. In such situations, treatment with hyperbaric oxygen accelerates the process of primary revascularization of full-thickness skin grafts and large composite grafts. Augmentation of capillary budding occurs because hyperbaric oxygen therapy raises the tissue oxygen tension in hypoxic areas to the level needed for extracellular deposition of collagen, which is needed for support of endothelial cells. Hyperbaric oxygen also appears to improve the survival of ischemic skin flaps of the face, although the exact mechanism of this action is unclear. Since 1982, a total of six patients needing periorbital reconstruction has been treated postoperatively with adjunct hyperbaric oxygen. Although the results have been uniformly favorable, a matched series comparing the results with and without hyperbaric oxygen therapy will be required to prove the efficacy of this treatment regimen.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 blood scispacy 1
해부 periorbital scispacy 1
해부 lid scispacy 1
해부 skin grafts scispacy 1
해부 grafts scispacy 1
해부 capillary scispacy 1
해부 tissue oxygen tension scispacy 1
해부 extracellular scispacy 1
해부 endothelial cells scispacy 1
합병증 periorbital scispacy 1
합병증 scar scispacy 1
약물 oxygen C0030054
oxygen
scispacy 1
약물 hyperbaric oxygen scispacy 1
기타 collagen scispacy 1
기타 skin flaps scispacy 1
기타 patients scispacy 1

MeSH Terms

Adolescent; Adult; Eyelids; Face; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Skin Transplantation; Surgery, Plastic; Surgical Flaps; Wound Healing