Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia.
💡 한 문장 핵심
안드로겐성 탈모 치료에서 혈소판 풍부 혈장(PRP)의 효능을 평가하기 위한 무작위 위약 대조, 이중맹검, 반두피 연구.
무작위 임상시험
4/5 보강
TL;DR
Application of PRP showed a positive effect on AGA and could be regarded as an adjuvant therapy for AGA and a correlation between anagen hairs and patients >40 years and beginning of AGA was found.
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
25 patients with AGA.
I · Intervention 중재 / 시술
a total of 3 treatments of PRP, 1 month apart
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
For the first time, the authors found a correlation between anagen hairs and patients >40 years and beginning of AGA ≥25 years old (p < .05) and hair density and male sex, age ≤40 years, positive family history of AGA and >10 years of duration of the disease (p < 0.05). [CONCLUSION] Application of PRP showed a positive effect on AGA and could be regarded as an adjuvant therapy for AGA.
📑 코퍼스 인용 관계
· 인용됨 39
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연도별 인용 (2016–2026) · 합계 229
OpenAlex 토픽 ·
Hair Growth and Disorders
Facial Rejuvenation and Surgery Techniques
Periodontal Regeneration and Treatments
Abstract 🌐 Abstract
[BACKGROUND] Platelet-rich plasma (PRP) was identified as having a beneficial effect in alopecia and has been postulated as a new therapy for androgenetic alopecia (AGA).
[OBJECTIVE] To assess the efficacy of PRP for the treatment of AGA.
[MATERIALS AND METHODS] This was a randomized, placebo-controlled, double-blind study in 25 patients with AGA. Platelet-rich plasma was injected in half-head and the other half-head with placebo. Each patient received a total of 3 treatments of PRP, 1 month apart.
[RESULTS] Six months after the first treatment with PRP, significant differences were seen in mean anagen hairs (67.6 ± 13.1), telogen hairs (32.4 ± 13.1), hair density (179.9 ± 62.7), and terminal hair density (165.8 ± 56.8) when compared with baseline (p < .05). Platelet-rich plasma was also found to increase hair density when comparing with the control side (p < .05). For the first time, the authors found a correlation between anagen hairs and patients >40 years and beginning of AGA ≥25 years old (p < .05) and hair density and male sex, age ≤40 years, positive family history of AGA and >10 years of duration of the disease (p < 0.05).
[CONCLUSION] Application of PRP showed a positive effect on AGA and could be regarded as an adjuvant therapy for AGA.
[OBJECTIVE] To assess the efficacy of PRP for the treatment of AGA.
[MATERIALS AND METHODS] This was a randomized, placebo-controlled, double-blind study in 25 patients with AGA. Platelet-rich plasma was injected in half-head and the other half-head with placebo. Each patient received a total of 3 treatments of PRP, 1 month apart.
[RESULTS] Six months after the first treatment with PRP, significant differences were seen in mean anagen hairs (67.6 ± 13.1), telogen hairs (32.4 ± 13.1), hair density (179.9 ± 62.7), and terminal hair density (165.8 ± 56.8) when compared with baseline (p < .05). Platelet-rich plasma was also found to increase hair density when comparing with the control side (p < .05). For the first time, the authors found a correlation between anagen hairs and patients >40 years and beginning of AGA ≥25 years old (p < .05) and hair density and male sex, age ≤40 years, positive family history of AGA and >10 years of duration of the disease (p < 0.05).
[CONCLUSION] Application of PRP showed a positive effect on AGA and could be regarded as an adjuvant therapy for AGA.
- p-value p < .05
Application of PRP showed a positive effect on AGA and could be regarded as an adjuvant therapy for AGA and a correlation between anagen hairs and patients >40 years and beginning of AGA was found.
APA 7
Alves, R., & Grimalt, R. (2016). Randomized placebo-controlled, double-blind, half-head study to assess the efficacy of platelet-rich plasma on the treatment of androgenetic alopecia.. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 42(4), 491-7. https://doi.org/10.1097/DSS.0000000000000665
Vancouver
Alves R, Grimalt R. Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia. Derm. surg. : offi. publ. Amer. Soci. Derm. Surg. [et al.]. 2016;42(4):491-7. doi:10.1097/DSS.0000000000000665
AMA 11
Alves R, Grimalt R. Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia. Derm. surg. : offi. publ. Amer. Soci. Derm. Surg. [et al.]. 2016;42(4):491-7. doi:10.1097/DSS.0000000000000665
Chicago
Alves, R., and Grimalt, R.. 2016. "Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia." Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 42 (4): 491-7. https://doi.org/10.1097/DSS.0000000000000665
MLA 9
Alves, R., and Grimalt R. "Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia." Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], vol. 42, no. 4, 2016, pp. 491-7. doi:10.1097/DSS.0000000000000665.
PMID
27035501 ↗
추출된 의학 개체 (NER)
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 질환 | androgenetic alopecia
|
안드로겐성 탈모 | dict | 2 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 7/8 (88%)
· 참조 0편 · 후속 7편
이 논문을 인용한 후속 연구 20
- Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considera…
- Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Fina…
- Alopecia Areata: Current Treatments and New Directions.
- Platelet-rich plasma for androgenetic alopecia: A review of the literature and proposed treatment pr…
- Effectiveness of Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature.
- Conventional and novel stem cell based therapies for androgenic alopecia.
- Advances in hair growth.
- Platelet-rich plasma for the treatment of alopecia: a systematic review and meta-analysis.
- Status of research on the development and regeneration of hair follicles.
- Platelet-rich Plasma for Androgenetic Alopecia Treatment: A Randomized Placebo-controlled Pilot Stud…
- Efficacy of Platelet-Rich Plasma and Concentrated Growth Factor in Treating Androgenetic Alopecia - …
- A Meta-analysis On Evidence Of Platelet-rich Plasma for Androgenetic Alopecia.
- Platelet-Rich Plasma with Microneedling in Androgenetic Alopecia: Study of Efficacy of the Treatment…
- Clinical Use of Extracellular Vesicles in the Management of Male and Female Pattern Hair Loss: A Pre…
- Human Hair Outer Root Sheath Cells and Platelet-Lysis Exosomes Promote Hair Inductivity of Dermal Pa…
- Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review.
- Current and emerging treatment strategies for hair loss in women of color.
- Effectiveness of Platelet-Rich Plasma in the Treatment of Androgenic Alopecia: A Meta-Analysis.
- Effectiveness of Platelet-Rich Plasma Therapy in Androgenic Alopecia-A Meta-Analysis.
- Investigating the Safety and Efficacy of Platelet-Rich Plasma (PRP) Treatment for Female Androgeneti…
같은 제1저자의 인용 많은 논문 (5)
- A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification.
- Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study.
- Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review.
- Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia.
- Hair loss in children.
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
📖 비슷한 OA 논문 — 같은 카테고리, 무료 전문 가능
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Epidemiology and burden of alopecia areata: a systematic review.
TL;DRAA is the most prevalent autoimmune disorder and the second most prevalent hair loss disorder after androgenetic alopecia, and the lifetime risk in the global population is approxi…
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Androgenetic alopecia: a review.
TL;DRA systematic review of the literature and candidate gene and genome-wide association studies have reported that single-nucleotide polymorphisms at different genomic loci are associ…
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Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.
TL;DRAlthough a variety of medical, surgical, light‐based and nutraceutical treatment options are available to slow or reverse the progression of AGA, it can be challenging to select ap…
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Minoxidil and its use in hair disorders: a review.
TL;DRThis article aims to review and update current information on the pharmacology, mechanism of action, clinical efficacy, and adverse events of topical minoxidil.
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Androgenetic Alopecia: Therapy Update.
TL;DRThis comprehensive review discusses the evaluation of AGA and the mechanisms of action, costs, efficacies, and safety profiles of existing, alternative, and upcoming therapeutics f…