Long-term study of reactions to various silicone breast implants in rabbits.

Plastic and reconstructive surgery 1976 Vol.57(5) p. 637-49

Lilla JA, Vistnes LM

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Abstract

A long-term study of the fixation and the encapsulation of soft alloplastic implants in rabbits was done-with examination of the capsules at one, 6, 12, and 18 months. No evidence of hematoma, infection, or carcinogenesis was observed. The type of filling in the prosthesis had no demonstrable effect on the encapsulation. The mobility of the prostheses correlated directly with the capsules evoked by plain silicone, perforated silicone-backed, Dacron-backed, and polyurethane-covered prostheses (in order of decreasing mobility). A patch on the base of a given prosthesis did not influence the amount or character of the capsule formed around the remainder of that prosthesis. The results of this study are discussed in the light of past information, to point out the need for further basic research on these problems.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 breast 유방 dict 1
합병증 hematoma 혈종 dict 1
합병증 infection 감염 dict 1
약물 silicone C0037114
silicones
scispacy 1
질환 capsule scispacy 1
기타 rabbits scispacy 1

MeSH Terms

Animals; Biocompatible Materials; Breast; Evaluation Studies as Topic; Female; Foreign-Body Reaction; Male; Prostheses and Implants; Prosthesis Design; Rabbits; Silicones; Surgery, Plastic

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