External Nasal Reconstruction in Patients With Extranodal Natural Killer (NK)/T-cell Lymphoma, Nasal Type.

Cureus 2025 Vol.17(12) p. e99730

Ueda M, Nomura T, Sakakibara S

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Abstract

Extranodal NK/T-cell lymphoma, nasal type (ENKTL-NT), is a rare and aggressive lymphoma of NK or T-cell origin, characterized by necrotizing and destructive granulomatous lesions that primarily affect facial midline structures. In the head and neck region, it often leads to extensive destruction of soft tissue, bone, and cartilage, potentially resulting in external nasal deformity and necrosis. This study reports on nasal reconstruction and its clinical course in patients with ENKTL-NT. Two patients with ENKTL-NT, who achieved remission following chemoradiotherapy, underwent external nasal reconstruction. Both cases involved autologous tissue reconstruction. Although external nasal morphology improved in both cases, long-term follow-up revealed contracture and secondary deformity, suggesting that outcomes were not entirely satisfactory. Accurate assessment of the remaining nasal components-including soft tissue and skeletal framework-is critical for selecting an appropriate reconstructive strategy.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 Nasal scispacy 1
해부 T-cell scispacy 1
해부 soft tissue scispacy 1
해부 bone scispacy 1
해부 cartilage scispacy 1
해부 tissue scispacy 1
해부 skeletal scispacy 1
합병증 Nasal Type scispacy 1
합병증 nasal components-including scispacy 1
합병증 necrosis 괴사 dict 1
질환 Extranodal Natural Killer (NK)/T-cell Lymphoma scispacy 1
질환 Extranodal NK/T-cell lymphoma C5420078
Sinonasal Extranodal NK/T-Cell Lymphoma
scispacy 1
질환 aggressive lymphoma scispacy 1
질환 necrotizing C0439664
Necrotizing
scispacy 1
질환 granulomatous lesions C3854000
Granulomatous lesion
scispacy 1
질환 nasal deformity C0240547
Deformity of the nose
scispacy 1
질환 contracture C0009917
Contracture
scispacy 1
질환 lymphoma scispacy 1
질환 head and neck scispacy 1
기타 Patients scispacy 1
기타 nasal scispacy 1

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