Cross-Cultural Adaptation and Clinical Application of the Russian Version of SEPEQoL Questionnaire.

[OBJECTIVES] Nasal septal perforation (NSP) significantly impacts quality of life (QoL), but no validated Russian-language instrument existed for comprehensive symptom assessment. This study aimed to translate, culturally adapt, and validate the SEPEQoL questionnaire for Russian-speaking populations.

[METHODS] Following ISPOR guidelines, the SEPEQoL was translated into Russian and administered to 30 NSP patients and 30 matched controls. Psychometric properties were evaluated, including internal consistency (Cronbach's α), test-retest reliability (intraclass correlation coefficient [ICC]), and discriminant validity. Surgical outcomes were assessed using validated SEPEQoL in patients undergoing endoscopic septal perforation repair with bilateral mucosal flaps and interposition cartilaginous graft.

[RESULTS] The Russian SEPEQoL demonstrated excellent reliability (α = 0.985, ICC = 0.98) and strong discriminant validity (21.6 ± 6.4 vs. 4.4 ± 3.9 in controls, p < 0.01). Postoperative scores improved dramatically (Δ = 15.4 points, d = 2.23, p < 0.001), with 100% resolution of whistling (δ = 0.95) and 94% improvement in crusting. Esthetic concerns showed minimal change (δ = 0.08, p = 0.32), underscoring the need for adjunct rhinoplasty in select cases. Patient age, gender, and perforation size did not impact outcomes.

[CONCLUSION] The Russian SEPEQoL is a valid, reliable tool that captures both functional and esthetic outcomes of NSP repair. Its implementation facilitates standardized outcome assessment and highlights persistent challenges in managing external nasal deformities.