Emergence agitation in open rhinoplasty operations neutrophil/lymphocyte and platelet/lymphocyte ratio as a predictive marker.

[OBJECTIVE] We aimed to evaluate the relationship between emergence agitation and pre-operative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) after rhinoplasty.

[METHODS] Our study included 104 patients. All patients underwent surgery under standard general anesthesia. In the pre-operative period, receiver operating curve analysis was performed to determine the cutoff values of NLR and PLR for the risk of emergence agitation and pre-operative anxiety. A correlation analysis was performed between NLR and PLR, the State-Trait Anxiety Inventory scale, and the body image disturbance scale.

[RESULTS] While the area under the curve (AUC) value of NLR for emergence agitation was not significant (p = 0.76), the cutoff value for PLR was 113.37 (AUC = 0.624, sensitivity = 80.65%, specificity = 45.21%, p = 0.046). Median PLR values were higher in patients with emergence agitation (p = 0.046). The AUC value for pre-operative anxiety was not significant. There was no correlation between NLR and PLR and the scales assessed.

[CONCLUSIONS] We suggest that PLR may be a predictive biomarker in evaluating the risk of pre-operative emergence agitation in patients scheduled for rhinoplasty.