An Algorithm for Control of Excessive Perioperative Bleeding and Ecchymosis in Rhinoplasty Patients Based on 4 Decades of Experience.

Plastic and reconstructive surgery 2025 Vol.155(1) p. 35e-43e

Guyuron B, Cakmakoglu C, Avasarala V

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Abstract

[BACKGROUND] Persistent intraoperative bleeding, excessive postoperative ecchymosis, epistaxis, and blood collection in the supratip area increase the complexity of rhinoplasty, causing suboptimal outcomes. The authors present an intraoperative bleeding management algorithm, developed by the senior author (B.G.) based on 43 years of experience, and assess its efficacy in achieving hemostatic control through 103 consecutive cases.

[METHODS] A retrospective chart review was conducted on 103 consecutive patients who had undergone septorhinoplasty performed by a single surgeon. The authors reviewed patient demographics; coagulopathies; medications; diet; intraoperative use of tranexamic acid (TXA), deamino-8- d -arginine vasopressin (DDAVP), and vitamin K; and postoperative complications.

[RESULTS] Twenty-six patients (25.2%) did not receive intraoperative hemostatic agents. Twenty-six patients (25.2%) required TXA only, 3 patients (2.91%) were given DDAVP only, 1 patient (0.97%) received vitamin K only, and 46 patients (44.7%) required both TXA and DDAVP. One patient (0.97%) needed TXA, DDAVP, and vitamin K. Intraoperative bleeding was controlled in all patients. One patient with known factor 11 deficiency received both TXA and DDAVP intraoperatively but did not require fresh frozen plasma. Intraoperative bleeding was controlled by first administering 10 mg/kg of TXA intravenously, followed by DDAVP with a maximum dose of 0.3 µg if needed, and 10 mg of vitamin K if bleeding persisted. Patients with known type I or IIa von Willebrand disease received DDAVP preoperatively. No patient experienced postoperative epistaxis, thromboembolism, or other associated complications.

[CONCLUSION] The algorithm of TXA, DDAVP, and vitamin K is effective in controlling excessive intraoperative bleeding, postoperative ecchymosis, and epistaxis.

[CLINICAL QUESTION/LEVEL OF EVIDENCE] Therapeutic, IV.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
약물 txa 트라넥삼산 dict 7
시술 rhinoplasty 코성형술 dict 2
시술 septorhinoplasty 코성형술 dict 1
해부 blood scispacy 1
약물 tranexamic acid 트라넥삼산 dict 1
약물 -arginine vasopressin C0003779
argipressin
scispacy 1
약물 DDAVP → deamino-8- d -arginine vasopressin scispacy 1
약물 vitamin K C0042878
vitamin K
scispacy 1
약물 vitamin K. C0042890
Vitamins
scispacy 1
약물 [BACKGROUND] scispacy 1
약물 TXA intravenously scispacy 1
질환 Ecchymosis C0013491
Ecchymosis
scispacy 1
질환 intraoperative bleeding scispacy 1
질환 epistaxis C0014591
Epistaxis
scispacy 1
질환 coagulopathies C0005779
Blood Coagulation Disorders
scispacy 1
질환 bleeding C0019080
Hemorrhage
scispacy 1
질환 Willebrand disease C0042974
von Willebrand Disease
scispacy 1
질환 postoperative epistaxis, thromboembolism scispacy 1
질환 postoperative ecchymosis scispacy 1
기타 Patients scispacy 1
기타 supratip area scispacy 1
기타 patient scispacy 1
기타 coagulopathies scispacy 1
기타 IIa von scispacy 1

MeSH Terms

Humans; Rhinoplasty; Ecchymosis; Retrospective Studies; Algorithms; Female; Male; Adult; Blood Loss, Surgical; Middle Aged; Young Adult; Hemostatics; Adolescent; Tranexamic Acid; Postoperative Hemorrhage

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