Use of 5-Fluorouracil for Management of the Thick-Skinned Nose.
Abstract
Patients with a thick nasal skin and soft tissue envelope can have unpredictable results and irregular scarring after rhinoplasty surgery. These patients typically have sebaceous tissue over the nasal tip and are particularly susceptible to soft tissue polly beak formation and excess scar tissue in the radix, tip, and septum. Targeted injections of 5-fluorouracil alone or mixed with low concentrations of steroid can be useful to prevent and treat excess postoperative scar tissue deposition. Ideally, four to six injections are performed every 1 to 4 weeks beginning 1 week postoperatively. The injections are most beneficial when performed within the first 3 months after surgery. Even a single injection may improve outcomes with minimal side effects.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | rhinoplasty
|
코성형술 | dict | 1 | |
| 해부 | Nose
|
scispacy | 1 | ||
| 해부 | soft tissue
|
scispacy | 1 | ||
| 해부 | sebaceous tissue
|
scispacy | 1 | ||
| 해부 | soft tissue polly
|
scispacy | 1 | ||
| 해부 | tissue
|
scispacy | 1 | ||
| 해부 | scar tissue
|
scispacy | 1 | ||
| 해부 | nasal tip
|
코끝 | dict | 1 | |
| 해부 | tip
|
코끝 | dict | 1 | |
| 해부 | septum
|
비중격 | dict | 1 | |
| 합병증 | nasal skin
|
scispacy | 1 | ||
| 약물 | 5-Fluorouracil
|
C0016360
fluorouracil
|
scispacy | 1 | |
| 약물 | steroid
|
C0038317
Steroids
|
scispacy | 1 | |
| 기타 | Patients
|
scispacy | 1 |
MeSH Terms
Adult; Cicatrix; Cohort Studies; Esthetics; Female; Fluorouracil; Follow-Up Studies; Humans; Injections, Intradermal; Injections, Intralesional; Male; Middle Aged; Postoperative Care; Postoperative Complications; Preoperative Care; Retrospective Studies; Rhinoplasty; Risk Assessment; Skin; Treatment Outcome
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