Bacterial cellulose as a new graft model for the Turkish delight technique in rhinoplasty: An experiment in 20 rats.

Ear, nose, & throat journal 2017 Vol.96(9) p. E1-E5

Aydinli S, Bişkin S, Dinç AE, Uçal YO, Kandemir N, Tekin İÖ

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Abstract

We conducted an experiment to investigate the effectiveness of bacterial cellulose, a new graft material, in correcting and preventing dorsal nasal disorder in rhinoplasty. The experiment was performed on 20 Wistar albino rats. The rats were evenly divided into two groups: a fascia group and a cellulose group. In the fascia group, grafts from the conchal cartilage were removed, shredded, and then wrapped in temporal muscle fascia. In the cellulose group, shredded cartilage was wrapped in the bacterial cellulose. These shredded gristle grafts, which were also placed in a subcutaneous area at the back of the rats, were excised after 60 days. We then performed histopathology to compare the health and integrity of the cartilage and the degree of vascularization, fibrosis, and chronic inflammation in the two groups. We found a significantly greater degree of vascularization (p = 0.004) and fibrosis (p = 0.005) in the fascia group and a significantly greater degree of chronic inflammation (p = 0.023) in the cellulose group. We found no statistically significant difference between the two groups in terms of cartilage health and integrity. Our results suggest that bacterial cellulose grafting may play a role as an alternative to fascia grafting for the wrapping of shredded cartilages in Turkish delight grafting, but further investigation is needed.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 rhinoplasty 코성형술 dict 2
해부 subcutaneous 피하조직 dict 1
해부 graft scispacy 1
해부 fascia scispacy 1
해부 grafts scispacy 1
해부 cartilage scispacy 1
해부 muscle fascia scispacy 1
해부 cartilages scispacy 1
재료 conchal cartilage 이개연골 dict 1
약물 cellulose scispacy 1
질환 nasal disorder C0028432
Nose Diseases
scispacy 1
질환 temporal muscle fascia scispacy 1
질환 fibrosis C0016059
Fibrosis
scispacy 1
질환 inflammation C0021368
Inflammation
scispacy 1
기타 rats scispacy 1
기타 dorsal nasal scispacy 1
기타 Wistar albino rats scispacy 1
기타 fascia scispacy 1

MeSH Terms

Animals; Bacteria; Cellulose; Fascia; Nasal Cartilages; Rats; Rats, Wistar; Rhinoplasty; Tissue Engineering; Treatment Outcome

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