Combination of microneedling and 10% trichloroacetic acid peels in the management of infraorbital dark circles.

Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology 2016 Vol.18(5) p. 289-92

Kontochristopoulos G, Kouris A, Platsidaki E, Markantoni V, Gerodimou M, Antoniou C

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Abstract

[BACKGROUND] Dark circles (DC), seen in the periorbital area, are defined as bilateral, round, homogeneous pigmented macules whose aetiology is thought to be multifactorial. Available treatments include bleaching creams, topical retinoic acid, chemical peels, lasers, autologous fat transplantation, injectable fillers and surgery (blepharoplasty).

[OBJECTIVE] To evaluate the efficacy and safety of a combination of microneedling and 10% trichloroacetic acid (TCA) peels in the treatment of DC.

[MATERIALS AND METHODS] Thirteen female patients with mild to severe infraorbital DC were included in the study. The patients were aged between 21 and 61 years. They were treated with Automatic Microneedle Therapy System-Handhold and topical application of 10% TCA solution to each infraorbital area for five minutes. The effect was photo-documented and a Patient and Physician Global Assessment was evaluated. Safety was assessed by evaluating early and delayed adverse events.

[RESULTS] Almost all patients showed significant aesthetic improvement. Both Physician and Patient Global Assessment rated a fair, good or excellent response in 92.3%. The procedure was well tolerated. Mild discomfort, transient erythema and oedema were quite common during or immediately after the procedure. The patients were followed up regularly every month for four months, and no recurrence was recorded.

[CONCLUSION] Microneedling and 10% TCA constitute an innovative combination treatment for DC with encouraging results and minor side effects.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 blepharoplasty 안검성형술 dict 1
해부 peels scispacy 1
해부 infraorbital scispacy 1
해부 fat scispacy 1
합병증 periorbital area scispacy 1
합병증 erythema scispacy 1
합병증 oedema scispacy 1
약물 trichloroacetic acid C0040900
trichloroacetic acid
scispacy 1
약물 retinoic acid C0040845
tretinoin
scispacy 1
약물 TCA → trichloroacetic acid C0040900
trichloroacetic acid
scispacy 1
약물 Microneedling scispacy 1
약물 [BACKGROUND] Dark scispacy 1
약물 [OBJECTIVE] scispacy 1
질환 erythema C0041834
Erythema
scispacy 1
질환 oedema C0013604
Edema
scispacy 1
질환 Physician scispacy 1
기타 patients scispacy 1
기타 Patient scispacy 1

MeSH Terms

Adult; Chemexfoliation; Facial Dermatoses; Female; Humans; Hyperpigmentation; Middle Aged; Needles; Orbit; Pain Measurement; Treatment Outcome; Trichloroacetic Acid

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