Morphea of the breast. Two case reports and discussion of the literature.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS 2006 Vol.59(10) p. 1114-7

Dancey AL, Waters RA

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Abstract

[UNLABELLED] Morphea, or localised scleroderma, is characterised by excess collagen deposition by lesional fibroblasts. This results in thickening and induration of the skin and subcutaneous tissues, often causing considerable morbidity. Radiation-induced morphea was mentioned as early as the 1900s, but since then awareness of this condition has declined. The incidence of radiation-induced morphea is said to be two in 1000. Extension of the morphea beyond the radiation ports occurs in approximately one quarter of cases. No proven effective treatments exist, and to our knowledge, surgical excision has not been attempted.

[CASE PRESENTATIONS] We present two cases of morphea of the breast. The first patient developed progressive morphea in the absence of any causative factors. This was treated by Wise pattern breast reduction, incorporating the morphea within the excised skin. The second patient developed morphea following a course of radiotherapy for breast carcinoma. She has declined any surgical intervention, but suffers from considerable morbidity. Morphea is a recognised sequelae of radiotherapy which should be distinguished from sclerotic recurrence of the original tumour. Surgical excision is possible in certain patients.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 breast 유방 dict 4
시술 breast reduction 유방성형술 dict 1
해부 skin scispacy 1
해부 subcutaneous tissues scispacy 1
해부 subcutaneous 피하조직 dict 1
질환 Morphea of the breast scispacy 1
질환 Morphea C0036420
Localized scleroderma
scispacy 1
질환 breast carcinoma C0678222
Breast Carcinoma
scispacy 1
질환 tumour C0027651
Neoplasms
scispacy 1
질환 lesional fibroblasts scispacy 1
기타 collagen scispacy 1
기타 patient scispacy 1
기타 Wise pattern breast scispacy 1
기타 patients scispacy 1

MeSH Terms

Adult; Breast Diseases; Breast Neoplasms; Female; Humans; Middle Aged; Radiation Injuries; Radiotherapy, Adjuvant; Scleroderma, Localized

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