Biostimulatory Fillers to Treat Post-liposuction Skin Irregularities.

[BACKGROUND] Treatment of post-liposuction skin irregularities (PLSI), a complication of liposuction, can be challenging.

[OBJECTIVE] Considering the increasing request of treatment of PLSI, the aim of this study is to evaluate the efficacy and safety of CaHA diluted/hyperdiluted to PLSI.

[METHODS] A retrospective study on a total of eight PLSI areas in six women treated with CaHA diluted/hyperdiluted was performed. Efficacy was estimated on pictures of affected areas collected before and four months after treatment, according to the recently validated PLSI scale and Student's t-test for paired samples was performed to analyze data. Eventual adverse events were used to evaluate safety.

[RESULTS] Our results showed a statistically significant improvement of number and depth of depressions and a trend toward reduction of skin laxity.

[CONCLUSION] This study reported the efficacy and safety of CaHA diluted/hyperdiluted for PLSI treatment. Larger studies are encouraged to support the results of this pilot study.