Chemically Defined, Clinical-Grade Cryopreservation of Human Adipose Stem Cells.

Methods in molecular biology (Clifton, N.J.) 2021 Vol.2180() p. 555-567

López M, Eroglu A

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Abstract

Adipose-derived stem cells (ASCs) reside in the stromal compartment of adipose tissue and can be easily harvested in large quantities through a clinically safe liposuction procedure. ASCs do not induce immunogenic reactions and rather exert immunosuppressive effects. Therefore, they can be used for both autologous and allogeneic transplantations. They hold great promise for cell-based therapies and tissue engineering. A prerequisite to the realization of this promise is the development of successful cryopreservation methods for ASCs. In this chapter, we describe a xeno-free- and chemically defined cryopreservation protocol, which can be used for various clinical applications of ASCs.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 liposuction 지방흡입 dict 1
해부 Adipose-derived stem cells scispacy 1
해부 ASCs → Adipose-derived stem cells scispacy 1
해부 adipose tissue scispacy 1
해부 tissue scispacy 1
약물 xeno-free- scispacy 1
질환 stromal compartment scispacy 1
질환 transplantations scispacy 1
기타 Human Adipose Stem Cells scispacy 1

MeSH Terms

Adipocytes; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cryopreservation; Cryoprotective Agents; Humans; Stem Cells; Tissue Engineering

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