Atenolol prevents the formation of expansive hematoma after rhytidoplasty.
Abstract
[OBJECTIVE] To evaluate the perioperative use of atenolol in reducing the incidence of hematoma after rhytidoplasty.
[METHODS] Between January 2007 and February 2013, 80 patients were randomized into two groups: Group A (n = 26) received perioperative atenolol in order to maintain heart rate (PR) around 60 per minute; Group B (n = 54) did not receive atenolol. Both groups underwent the same anesthetic and surgical technique. We monitored blood pressure (BP), HR, hematoma formation and the need for drainage. Patients were followed-up until the 90th postoperative day. The variables were compared between the groups using the ANOVA test. Continuous variables were presented as mean ± standard deviation and the differences were compared with the Student's t test. Values of p d" 0.05 were considered significant.
[RESULTS] In group A the mean BP (110-70 mm Hg ± 7.07) and HR (64 / min ± 5) were lower (p d" 0.05) than in group B (135-90 mm Hg ± 10.6) and (76 / min ± 7.5), respectively. There were four cases of expansive hematoma in group B, all requiring reoperation for drainage, and none in group A (p d" 0,001).
[CONCLUSION] The perioperative use of atenolol caused a decrease in blood pressure and heart rate and decreased the incidence of expanding hematoma after rhytidectomy.
[METHODS] Between January 2007 and February 2013, 80 patients were randomized into two groups: Group A (n = 26) received perioperative atenolol in order to maintain heart rate (PR) around 60 per minute; Group B (n = 54) did not receive atenolol. Both groups underwent the same anesthetic and surgical technique. We monitored blood pressure (BP), HR, hematoma formation and the need for drainage. Patients were followed-up until the 90th postoperative day. The variables were compared between the groups using the ANOVA test. Continuous variables were presented as mean ± standard deviation and the differences were compared with the Student's t test. Values of p d" 0.05 were considered significant.
[RESULTS] In group A the mean BP (110-70 mm Hg ± 7.07) and HR (64 / min ± 5) were lower (p d" 0.05) than in group B (135-90 mm Hg ± 10.6) and (76 / min ± 7.5), respectively. There were four cases of expansive hematoma in group B, all requiring reoperation for drainage, and none in group A (p d" 0,001).
[CONCLUSION] The perioperative use of atenolol caused a decrease in blood pressure and heart rate and decreased the incidence of expanding hematoma after rhytidectomy.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 합병증 | hematoma
|
혈종 | dict | 5 | |
| 시술 | rhytidectomy
|
안면거상술 | dict | 1 | |
| 해부 | heart
|
scispacy | 1 | ||
| 해부 | blood
|
scispacy | 1 | ||
| 해부 | HR (64
|
scispacy | 1 | ||
| 약물 | Atenolol
|
C0004147
atenolol
|
scispacy | 1 | |
| 약물 | [OBJECTIVE]
|
scispacy | 1 | ||
| 약물 | [RESULTS]
|
scispacy | 1 | ||
| 기타 | patients
|
scispacy | 1 | ||
| 기타 | B (135-
|
scispacy | 1 |
MeSH Terms
Adrenergic beta-1 Receptor Antagonists; Atenolol; Female; Hematoma; Humans; Male; Middle Aged; Postoperative Complications; Prospective Studies; Rhytidoplasty
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