Preoperative use of alpha tocopherol does not increase the risk of hematoma in the face lift patient: a preliminary report.

Plastic and reconstructive surgery 2009 Vol.124(5) p. 1696-1699

Ristow B

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Abstract

[BACKGROUND] Antiplatelet therapy and nutritional supplements are factors that may increase the risk of hematoma after routine face lift. This has led to the often-repeated instruction "do not take any vitamins, herbs, aspirin, and any medications that may increase bleeding for 10 days before your face lift operation." At odds and diametrically opposed to this goal is combating the increased risk of deep venous thrombosis and venous thromboembolism associated with surgery.

[METHODS] On the basis of clinical observations, the author has incorporated the routine use of preoperative oral alpha tocopherol (vitamin E) into his preoperative instructions. The cohort included 146 patients scheduled for elective face lift enrolled in this study from February of 2007 to April of 2008. Aspirin and clopidogrel were stopped before surgery. Patients were instructed to take 400 IU of alpha tocopherol daily 3 weeks before surgery.

[RESULTS] No hematoma developed in any of the 146 patients. The time for routine drainage was not prolonged. No clinically evident case of deep vein thrombosis or venous thromboembolism occurred. The clinical impression was that increased bruising was not observed.

[CONCLUSIONS] A recent landmark article has documented the efficacy of alpha tocopherol in the prevention of venous thromboembolism in over 39,000 patients. The addition of this readily available, over-the-counter medication may have profound effects in the prevention of a potentially devastating complication in the elective cosmetic surgery patient. Future prospective studies may further elucidate the efficacy of alpha tocopherol in the prevention of venous thromboembolism.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 face lift 안면거상술 dict 4
합병증 hematoma 혈종 dict 3
합병증 oral alpha scispacy 1
합병증 bruising scispacy 1
약물 tocopherol C0042874
vitamin E
scispacy 1
약물 vitamins C0042890
Vitamins
scispacy 1
약물 aspirin C0004057
aspirin
scispacy 1
약물 oral alpha tocopherol C0969677
alpha tocopherol
scispacy 1
약물 vitamin E C0042874
vitamin E
scispacy 1
약물 clopidogrel C0070166
clopidogrel
scispacy 1
약물 alpha tocopherol scispacy 1
약물 [BACKGROUND] scispacy 1
약물 alpha tocopherol daily 3 scispacy 1
약물 [CONCLUSIONS] A scispacy 1
질환 bleeding C0019080
Hemorrhage
scispacy 1
질환 venous thrombosis C0042487
Venous Thrombosis
scispacy 1
질환 venous thromboembolism C1861172
Venous Thromboembolism
scispacy 1
질환 vein thrombosis C0042487
Venous Thrombosis
scispacy 1
질환 bruising C0009938
Contusions
scispacy 1
기타 patient scispacy 1
기타 herbs scispacy 1
기타 venous scispacy 1
기타 patients scispacy 1

MeSH Terms

Aged; Drug Administration Schedule; Female; Hematoma; Humans; Incidence; Male; Middle Aged; Preoperative Period; Primary Prevention; Retrospective Studies; Rhytidoplasty; Treatment Outcome; Venous Thromboembolism; Vitamins; alpha-Tocopherol

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