Penicillamine-induced pseudoxanthoma elasticum-like skin changes requiring rhytidectomy.
Abstract
A 42-year-old woman with pronounced skin laxity of her neck underwent a rhytidectomy and was found to have pseudoxanthoma elasticum-like changes of her skin. Her medical history was significant for Wilson's disease, requiring that she take penicillamine for 26 years. In patients on long-term penicillamine therapy, 20% to 33% will develop a dermatopathy. The drug has been used to alter scar formation in various surgical conditions. Penicillamine is known to alter cross-linking of elastin and collagen fibers. A review of the literature reveals other penicillamine-related dermatopathies that may present to the surgeon.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | rhytidectomy
|
안면거상술 | dict | 2 | |
| 해부 | skin
|
scispacy | 1 | ||
| 합병증 | dermatopathy
|
scispacy | 1 | ||
| 합병증 | scar
|
scispacy | 1 | ||
| 약물 | penicillamine
|
C0030817
penicillamine
|
scispacy | 1 | |
| 질환 | Penicillamine-induced pseudoxanthoma elasticum-like skin
|
scispacy | 1 | ||
| 질환 | pseudoxanthoma
|
scispacy | 1 | ||
| 질환 | Wilson's disease
|
C0019202
Hepatolenticular Degeneration
|
scispacy | 1 | |
| 질환 | dermatopathy
|
C0037268
Skin Abnormalities
|
scispacy | 1 | |
| 질환 | penicillamine-related dermatopathies
|
scispacy | 1 | ||
| 기타 | patients
|
scispacy | 1 | ||
| 기타 | elastin
|
scispacy | 1 | ||
| 기타 | collagen
|
scispacy | 1 |
MeSH Terms
Adult; Facial Dermatoses; Female; Humans; Neck; Penicillamine; Pseudoxanthoma Elasticum; Rhytidoplasty; Skin Aging
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