A plastic surgery approach to Meige syndrome: Botulinum toxin for rebalancing facial dystonia and aesthetics - A case report.

JPRAS open 2026 Vol.49() p. 342-348

Long X

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Abstract

Meige syndrome is a rare segmental dystonia characterized by blepharospasm and oromandibular dystonia, often leading to significant functional and aesthetic impairment. This report details a 59-year-old female patient with a 16-year history whose symptoms were refractory to prior drug therapies. An individualized botulinum toxin type A (BTX-A) injection protocol was devised based on detailed facial muscle mapping and plastic surgery principles of muscle balance. Following treatment, the patient showed marked improvement in facial spasms within 1 week, with resolution of nocturnal headaches and notable correction of aesthetic concerns arising from dystonia, including facial asymmetry and the involuntary "gummy smile". The gingival exposure during dystonic contraction was reduced from >4 mm (classified as severe gingival smile) to 1 mm. Social and eating functions were restored. This case suggests that a BTX-A treatment strategy guided by plastic surgery principles, which addresses both functional symptoms and aesthetic disharmony, may provide an effective and safe office-based treatment option for Meige syndrome. Further studies with larger cohorts are warranted to validate this protocol.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 2
해부 muscle scispacy 1
해부 gummy scispacy 1
합병증 asymmetry 비대칭 dict 1
합병증 facial scispacy 1
약물 BTX-A → botulinum toxin type A scispacy 1
질환 Meige syndrome C0025183
Meige Syndrome
scispacy 1
질환 dystonia C0013421
Dystonia
scispacy 1
질환 blepharospasm C0005747
Blepharospasm
scispacy 1
질환 oromandibular dystonia C2242577
Oromandibular dystonia
scispacy 1
질환 spasms C0037763
Spasm
scispacy 1
질환 headaches C0018681
Headache
scispacy 1
질환 dystonic contraction scispacy 1
질환 gingival smile scispacy 1
질환 aesthetics - A scispacy 1
기타 patient scispacy 1
기타 botulinum toxin type A scispacy 1

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