Feasibility and clinical value of pyloric functional luminal imaging probe in an infant.

JPGN reports 2026 Vol.7(1) p. 59-63

Porto A, Pantazopoulos RS, Osgood PT, Fortunato JE

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Abstract

Pyloric dysfunction is becoming increasingly recognized as a cause of gastroparesis, but its diagnostic and therapeutic role in infants has not been well studied. Identification and treatment of pyloric dysfunction with functional luminal imaging probe (FLIP) technology or use of pyloric inhibition are not routinely used in infants due to lack of standardized parameters and safety concerns. We report the first known case of pyloric distensibility testing in an infant in which identification of low pyloric distensibility and subsequent therapeutic balloon dilatation and intrapyloric botulinum toxin injection resulted in marked and sustained improvement in gastric feeding tolerance. This case highlights the feasibility, safety, and clinical effectiveness of FLIP as a diagnostic and treatment tool in an infant with pyloric dysfunction. Better characterization of infant pyloric distensibility offers the possibility of evidence-based treatment strategies for feeding intolerance attributed to pyloric dysfunction.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 1
해부 pyloric scispacy 1
합병증 pyloric distensibility scispacy 1
합병증 gastric feeding scispacy 1
합병증 pyloric scispacy 1
약물 luminal C0524462
Luminal region
scispacy 1
약물 intrapyloric botulinum toxin scispacy 1
질환 Pyloric dysfunction C0679410
pyloric dysfunction
scispacy 1
질환 gastroparesis C0152020
Gastroparesis
scispacy 1
기타 FLIP → functional luminal imaging probe scispacy 1

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