The Effect of Intravesical Injection of Botulinum Toxin A (BTX-A) on Quality of Life of Pediatrics Diagnosed With Overactive Bladder: A Quasi-Experimental Study.

Sage open pediatrics 2025 Vol.12() p. 30502225251346341

Al-Rimawi SM, Alrimawi I, Ibrahim MM, Oleimat B, Elayan AM, Khatatbeh H, Albikawi ZF, Saifan AR

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Abstract

[OBJECTIVES] To investigate the effectiveness of Botulinum Toxin A (BTX-A) intravesical injections in improving quality of life (QoL) among pediatric patients.

[INTRODUCTION] Overactive bladder (OAB) in children impacts their QoL. Current treatments often have limitations, necessitating the exploration of alternative therapies.

[METHODS] A quasi-experimental design was conducted in four Jordanian hospitals, with participants being parents of pediatric OAB patients aged 5 to 18 years. Statistical analysis was utilized for data analysis.

[RESULTS] Results showed that BTX-A injections significantly improved QoL scores for pediatric OAB patients, with marked reductions in symptoms and enhanced well-being in the intervention group. Key demographic factors like household income and age at symptom onset were linked to QoL outcomes, and pre-treatment QoL varied by healthcare provider type.

[CONCLUSION] This study highlights BTX-A as a promising therapeutic and advocates for its broader adoption in pediatric urology to enhance the well-being and daily functioning of children with OAB.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 2
해부 bladder scispacy 1
약물 BTX-A → Botulinum Toxin A scispacy 1
약물 [OBJECTIVES] scispacy 1
약물 [INTRODUCTION] Overactive scispacy 1
약물 OAB → Overactive bladder scispacy 1
질환 Overactive Bladder C0878773
Overactive Bladder
scispacy 1
질환 OAB → Overactive bladder C0878773
Overactive Bladder
scispacy 1
질환 reductions in symptoms and enhanced well-being in the intervention group. scispacy 1
질환 Bladder: A Quasi-Experimental scispacy 1
기타 Botulinum Toxin A scispacy 1
기타 patients scispacy 1
기타 children scispacy 1
기타 participants scispacy 1

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