Effect of botulinum toxin type a combined with physical therapy on functional capacity in children with spastic cerebral palsy: a randomized controlled clinical trial.
Abstract
[OBJECTIVE] Investigate the effects of botulinum toxin type A (BoNT-A) combined with physical therapy on functional capacity in children with spastic cerebral palsy (CP).
[METHODS] Twenty-four children with spastic CP were treated with either BoNT-A and physical therapy or physical therapy alone.
[RESULTS] Significant differences ( < 0.05) were found after 30 days of treatment for the Berg Scale, Timed Up and Go (TUG) test, Ashworth Scale and Pediatric Evaluation of Disability Inventory (PEDI) and after three months for the Berg Scale, TUG test and PEDI. No significant differences ( > 0.05) were found in the control group.
[DISCUSSION] BoNT-A combined with physical therapy leads to significant improvements in spasticity and functionality in children with CP within a period of three months from the onset of treatment.
[METHODS] Twenty-four children with spastic CP were treated with either BoNT-A and physical therapy or physical therapy alone.
[RESULTS] Significant differences ( < 0.05) were found after 30 days of treatment for the Berg Scale, Timed Up and Go (TUG) test, Ashworth Scale and Pediatric Evaluation of Disability Inventory (PEDI) and after three months for the Berg Scale, TUG test and PEDI. No significant differences ( > 0.05) were found in the control group.
[DISCUSSION] BoNT-A combined with physical therapy leads to significant improvements in spasticity and functionality in children with CP within a period of three months from the onset of treatment.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | botulinum toxin
|
보툴리눔독소 주사 | dict | 2 | |
| 해부 | cerebral
|
scispacy | 1 | ||
| 약물 | [OBJECTIVE]
|
scispacy | 1 | ||
| 약물 | Berg
|
scispacy | 1 | ||
| 질환 | spastic cerebral palsy
|
C0338596
Spastic cerebral palsy
|
scispacy | 1 | |
| 질환 | spastic CP
|
C0443306
Spastic
|
scispacy | 1 | |
| 질환 | spasticity
|
C0026838
Muscle Spasticity
|
scispacy | 1 | |
| 기타 | botulinum toxin type
|
scispacy | 1 | ||
| 기타 | children
|
scispacy | 1 | ||
| 기타 | BoNT-A
→ botulinum toxin type A
|
scispacy | 1 | ||
| 기타 | Go (TUG)
|
scispacy | 1 |
MeSH Terms
Child; Child, Preschool; Female; Humans; Male; Botulinum Toxins, Type A; Cerebral Palsy; Combined Modality Therapy; Disability Evaluation; Muscle Spasticity; Neuromuscular Agents; Physical Therapy Modalities; Treatment Outcome
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