Sequelae Treatment Needs Following Peripheral Facial Palsy: Retrospective Analysis of 525 Patients.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2024 Vol.45(5) p. e450-e456

Ohm R, Stark B, Brännström F, Marsk E

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Abstract

[OBJECTIVE] This study uses retrospective longitudinal data from a large unselected cohort of patients with peripheral facial paralysis to determine the prevalence and patient characteristic predictors of sequelae receiving intervention.

[STUDY DESIGN] Retrospective case review.

[SETTING] Karolinska University Hospital in Stockholm Sweden serves as the only tertiary facial palsy center in the region. Here, patients are diagnosed, are followed up, and undergo all major interventions.

[PATIENTS] All adult patients presenting with peripheral facial palsy due to idiopathic, zoster, or Borrelia origin at Karolinska, January 1, 2010 to December 31, 2011 with follow-up until December 2022.

[INTERVENTIONS] Patient charts were studied to identify patient characteristics, etiology, initial treatment, severity of palsy, and treatments targeting sequelae.

[MAIN OUTCOME MEASURES] Types of initial and late treatments were noted. Sunnybrook and/or House-Brackmann scales were used for palsy grading.

[RESULTS] Five hundred twenty-five patients were included. Thirty-three patients (6.3%) received botulinum toxin injections and/or surgical treatment. In this subgroup, 67% received corticosteroids compared to 85% of all patients ( p = 0.005), cardiovascular disease prevalence was higher (23 and 42%, respectively, p = 0.009). For 81 patients (15%), follow-up was discontinued although the last measurement was Sunnybrook less than 70 or House-Brackmann 3 to 6.

[CONCLUSIONS] Of patients with peripheral facial palsy, 6.3% underwent injections and/or surgical treatment within 12 years. However, due to a rather large proportion not presenting for follow-up, this might be an underestimation. Patients receiving late injections and/or surgical treatment had more comorbidities and received corticosteroid treatment to a significantly lower extent in the acute phase of disease.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 1
해부 cardiovascular scispacy 1
합병증 Peripheral Facial scispacy 1
약물 [OBJECTIVE] scispacy 1
약물 [MAIN OUTCOME scispacy 1
약물 corticosteroids scispacy 1
약물 [CONCLUSIONS] scispacy 1
약물 corticosteroid scispacy 1
질환 Peripheral Facial Palsy scispacy 1
질환 paralysis C0522224
Paralysed
scispacy 1
질환 palsy C0522224
Paralysed
scispacy 1
질환 idiopathic, zoster scispacy 1
질환 cardiovascular disease C0007222
Cardiovascular Diseases
scispacy 1
질환 disease scispacy 1
기타 Patients scispacy 1
기타 patient scispacy 1

MeSH Terms

Humans; Male; Female; Retrospective Studies; Facial Paralysis; Middle Aged; Aged; Adult; Sweden; Aged, 80 and over; Herpes Zoster Oticus; Botulinum Toxins

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