Sequelae Treatment Needs Following Peripheral Facial Palsy: Retrospective Analysis of 525 Patients.
Abstract
[OBJECTIVE] This study uses retrospective longitudinal data from a large unselected cohort of patients with peripheral facial paralysis to determine the prevalence and patient characteristic predictors of sequelae receiving intervention.
[STUDY DESIGN] Retrospective case review.
[SETTING] Karolinska University Hospital in Stockholm Sweden serves as the only tertiary facial palsy center in the region. Here, patients are diagnosed, are followed up, and undergo all major interventions.
[PATIENTS] All adult patients presenting with peripheral facial palsy due to idiopathic, zoster, or Borrelia origin at Karolinska, January 1, 2010 to December 31, 2011 with follow-up until December 2022.
[INTERVENTIONS] Patient charts were studied to identify patient characteristics, etiology, initial treatment, severity of palsy, and treatments targeting sequelae.
[MAIN OUTCOME MEASURES] Types of initial and late treatments were noted. Sunnybrook and/or House-Brackmann scales were used for palsy grading.
[RESULTS] Five hundred twenty-five patients were included. Thirty-three patients (6.3%) received botulinum toxin injections and/or surgical treatment. In this subgroup, 67% received corticosteroids compared to 85% of all patients ( p = 0.005), cardiovascular disease prevalence was higher (23 and 42%, respectively, p = 0.009). For 81 patients (15%), follow-up was discontinued although the last measurement was Sunnybrook less than 70 or House-Brackmann 3 to 6.
[CONCLUSIONS] Of patients with peripheral facial palsy, 6.3% underwent injections and/or surgical treatment within 12 years. However, due to a rather large proportion not presenting for follow-up, this might be an underestimation. Patients receiving late injections and/or surgical treatment had more comorbidities and received corticosteroid treatment to a significantly lower extent in the acute phase of disease.
[STUDY DESIGN] Retrospective case review.
[SETTING] Karolinska University Hospital in Stockholm Sweden serves as the only tertiary facial palsy center in the region. Here, patients are diagnosed, are followed up, and undergo all major interventions.
[PATIENTS] All adult patients presenting with peripheral facial palsy due to idiopathic, zoster, or Borrelia origin at Karolinska, January 1, 2010 to December 31, 2011 with follow-up until December 2022.
[INTERVENTIONS] Patient charts were studied to identify patient characteristics, etiology, initial treatment, severity of palsy, and treatments targeting sequelae.
[MAIN OUTCOME MEASURES] Types of initial and late treatments were noted. Sunnybrook and/or House-Brackmann scales were used for palsy grading.
[RESULTS] Five hundred twenty-five patients were included. Thirty-three patients (6.3%) received botulinum toxin injections and/or surgical treatment. In this subgroup, 67% received corticosteroids compared to 85% of all patients ( p = 0.005), cardiovascular disease prevalence was higher (23 and 42%, respectively, p = 0.009). For 81 patients (15%), follow-up was discontinued although the last measurement was Sunnybrook less than 70 or House-Brackmann 3 to 6.
[CONCLUSIONS] Of patients with peripheral facial palsy, 6.3% underwent injections and/or surgical treatment within 12 years. However, due to a rather large proportion not presenting for follow-up, this might be an underestimation. Patients receiving late injections and/or surgical treatment had more comorbidities and received corticosteroid treatment to a significantly lower extent in the acute phase of disease.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | botulinum toxin
|
보툴리눔독소 주사 | dict | 1 | |
| 해부 | cardiovascular
|
scispacy | 1 | ||
| 합병증 | Peripheral Facial
|
scispacy | 1 | ||
| 약물 | [OBJECTIVE]
|
scispacy | 1 | ||
| 약물 | [MAIN OUTCOME
|
scispacy | 1 | ||
| 약물 | corticosteroids
|
scispacy | 1 | ||
| 약물 | [CONCLUSIONS]
|
scispacy | 1 | ||
| 약물 | corticosteroid
|
scispacy | 1 | ||
| 질환 | Peripheral Facial Palsy
|
scispacy | 1 | ||
| 질환 | paralysis
|
C0522224
Paralysed
|
scispacy | 1 | |
| 질환 | palsy
|
C0522224
Paralysed
|
scispacy | 1 | |
| 질환 | idiopathic, zoster
|
scispacy | 1 | ||
| 질환 | cardiovascular disease
|
C0007222
Cardiovascular Diseases
|
scispacy | 1 | |
| 질환 | disease
|
scispacy | 1 | ||
| 기타 | Patients
|
scispacy | 1 | ||
| 기타 | patient
|
scispacy | 1 |
MeSH Terms
Humans; Male; Female; Retrospective Studies; Facial Paralysis; Middle Aged; Aged; Adult; Sweden; Aged, 80 and over; Herpes Zoster Oticus; Botulinum Toxins
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