Botulinum Toxin Injections to the Obliquus Capitis Inferioris Muscle for Dynamic Cervical Dystonia Improves Subjective Patient Outcomes.

Toxins 2024 Vol.16(2)

Bessemer RA, Jog M

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Abstract

The obliquus capitis inferioris (OCI) muscle is a significant driver of cervical dystonia with torticaput movements and a no-no head tremor. Limited data are available on the efficacy of OCI injections on patient outcomes. Our study aims to determine whether the botulinum toxin injection into OCI improves subjective patient quality of life in those with dystonic head tremors. A retrospective chart review was performed for 25 patients receiving injections into the OCI for a dystonic head tremor at the London Movement Disorders Clinic between January 2020 and January 2022. Toronto Western Spasmodic Torticollis Scale-2 (TWSTRS-2) subscale scores for disability and pain, TWSTRS-PSYCH scores, and the global impression of severity were extracted. The average TWSTRS-2 disability subscale change was -2.8 points ( < 0.003). The average TWSTRS-2 pain subscale change was -4.6 points ( < 0.003). The average TWSTRS-PSYCH score prior to injection was 5.6. After injection, the average score was 3.7 ( < 0.004). The patient self-reported average global impression of severity before injection was 7.0; after this, it was 4.2 ( < 0.0003). The OCI injection showed significant improvement in retrospective patient self-reported outcomes; it should be considered early in the treatment plan for cervical dystonia with a no-no head tremor.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 2
해부 Cervical scispacy 1
해부 muscle scispacy 1
질환 Obliquus Capitis scispacy 1
질환 Dystonia C0013421
Dystonia
scispacy 1
질환 torticaput movements scispacy 1
질환 tremor C0040822
Tremor
scispacy 1
질환 dystonic head tremors scispacy 1
질환 dystonic head tremor C4314815
Dystonic head tremor
scispacy 1
질환 disability C0231170
Disability
scispacy 1
질환 pain C0030193
Pain
scispacy 1
질환 TWSTRS-2 disability scispacy 1
질환 Obliquus Capitis Inferioris Muscle scispacy 1
질환 head tremor scispacy 1
질환 head tremors scispacy 1
질환 TWSTRS-2 → Toronto Western Spasmodic Torticollis Scale-2 scispacy 1
기타 Botulinum Toxin Injections scispacy 1
기타 Patient scispacy 1
기타 obliquus capitis inferioris scispacy 1
기타 patients scispacy 1

MeSH Terms

Humans; Torticollis; Botulinum Toxins, Type A; Quality of Life; Retrospective Studies; Tremor; Muscle, Skeletal; Pain; Treatment Outcome; Neuromuscular Agents

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